Impact of Micronutrient Supplementation on Pesticide Residual, Acetylcholinesterase Activity, and Oxidative Stress Among Farm Children Exposed to Pesticides
Bibliographic Data
| ID | 22081392 |
|---|---|
| Authors | Srujana Medithi (0000-0001-9394-1974, Symbiosis International University), Yogeswar Dayal Kasa (Indian Council of Medical Research), Vijay Radhakrishna Kankipati (Indian Council of Medical Research), Venkaiah Kodali (Indian Council of Medical Research), Babban Jee (0000-0002-2530-1489, Government of India), Padmaja R Jonnalagadda (0000-0002-7215-8937, Indian Council of Medical Research, corresponding author) |
| Year | 2022 |
| Volume | 10 |
| Pages | 872125-872125 |
| Publication date | 2022-06-14 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2022.872125 |
| PMID | 35774575 |
| OpenAlex | W4282836007 |
| Language | EN |
| References cited | 40 |
The present interventional study aimed to assess the impact of micronutrient supplementation on pesticide-residues concentrations, vitamins, minerals, acetylcholinesterase activity and oxidative stress among 129 farm children (9–12 years, n = 66 and 13–15 years, n = 63) involved in farming activities in Ranga Reddy district, Telangana, India. Our data showed the presence of five organophosphorus pesticide residues (chlorpyrifos, diazinon, malathion, monocrotophos, and phosalone) among children before-supplementation (both age-groups); while post-supplementation, only two pesticide residues (chlorpyrifos and diazinon) were detected indicating improved metabolic rate. Vitamin E, copper, magnesium and zinc levels were also improved in both the age-groups and manganese levels were significantly increased only among children of 13–15 years age group. Further, post-supplementation also showed an improvement in acetylcholinesterase activity and a decrease in lipid peroxidation among both the age groups of children. However, further research for ascertaining the ameliorating effect of micronutrients in preventing adverse effects of organophosphorus pesticides must be conducted
Acetylcholinesterase · Agronomy · Biology · Chlorpyrifos · Diazinon · Dimethoate · Enzyme · Malathion · Micronutrient · Oxidative stress · Pesticide · Pesticide residue · Chemistry · Child Nutrition and Water Access · Pesticide Exposure and Toxicity · Vitamin C and Antioxidants Research · Biochemistry · Toxicology
| Highly cited | No |
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