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Association between ambient air pollution and outpatient visits of cardiovascular diseases in Zibo, China

A time series analysis

Bibliographic Data

ID22081817
AuthorsYamei Wang (0000-0003-3035-0178), Wang Yamei (Shandong University), S Qu (0009-0005-7738-7607, Shandong University), Ting Li (0000-0002-9614-1566, Shandong University), Liang Chen (0000-0003-1553-2846, Qilu Hospital of Shandong University), Liping Yang (0000-0002-2606-6740, Shandong University)
Year2025
Volume12
Pages1492056-1492056
Publication date2025-01-08
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2024.1492056
PMID39845652
OpenAlexW4406188669
LanguageEN
Citations received3
References cited54

Introduction Facing Mount Tai in the south and the Yellow River in the north, Zibo District is an important petrochemical base in China. The effect of air pollution on cardiovascular diseases (CVDs) in Zibo was unclear. Methods Daily outpatient visits of common CVDs including coronary heart disease (CHD), stroke, and arrhythmia were obtained from 2019 to 2022 in Zibo. Air pollutants contained fine particulate matter (PM 2.5 ), inhalable particulate matter (PM 10 ), nitrogen dioxide (NO 2 ), sulfur dioxide (SO 2 ), ozone (O 3 ), and carbon monoxide (CO). Distributed lag non-linear models (DLNM) including single-pollutant model in single-day (lag0-lag7) and cumulative-days (lag01-lag07), concentration-response curve, subgroup analysis, and double-pollutant model were utilized to examine the relationships of daily air pollutants on CHD, stroke, and arrhythmia. Meteorological factors were incorporated to control confounding. Results In single-pollutant model, NO 2 was positively associated with CHD, stroke and arrhythmia, with the strongest excess risks (ERs) of 4.97% (lag07), 4.71% (lag07) and 2.16% (lag02), respectively. The highest ERs of PM 2.5 on CHD, stroke and arrhythmia were 0.85% (lag01), 0.59% (lag0) and 0.84% (lag01), and for PM 10 , the ERs were 0.37% (lag01), 0.35% (lag0) and 0.39% (lag01). SO 2 on CHD was 0.92% (lag6), O 3 on stroke was 0.16% (lag6), and CO on CHD, stroke, and arrhythmia were 8.77% (lag07), 5.38% (lag01), 4.30% (lag0). No threshold was found between air pollutants and CVDs. The effects of ambient pollutants on CVDs (NO 2 &CVDs, PM 2.5 &stroke, PM 10 &stroke, CO&stroke, CO&arrhythmia) were greater in cold season than warm season. In double-pollutant model, NO 2 was positively associated with CHD and stroke, and CO was also positively related with CHD. Conclusion Ambient pollutants, especially NO 2 and CO were associated with CVDs in Zibo, China. And there were strong relationships between NO 2 , PM 2.5 , PM 10 , CO and CVDs in cold season

Air pollution · Biology · China · Environmental health · Geography · Air Quality and Health Impacts · Air Quality Monitoring and Forecasting · Heme Oxygenase-1 and Carbon Monoxide · Medicine

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Citations per year3
Citation span2025 - 2025 (1)
Highly citedNo

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