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The effect of air pollutants on COPD-hospitalized patients in Lanzhou, China (2015–2019)

Bibliographic Data

ID22081998
AuthorsLimei Jin (0000-0002-5378-2865, Gansu University of Traditional Chinese Medicine), Shuya Fang, Yaxing Nan (Gansu University of Traditional Chinese Medicine), Jihong Hu (0000-0003-0391-963X, Ministry of Education of the People's Republic of China, corresponding author), Hua Jin (0000-0002-2176-7556, Ministry of Education of the People's Republic of China, corresponding author)
Year2024
Volume12
Pages1399662-1399662
Publication date2024-09-19
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2024.1399662
PMID39363981
OpenAlexW4402656737
LanguageEN
References cited56

Background Lanzhou is the largest heavy industrial city in northwest China and it is a typical geographical valley-like city. However, there are few studies on the relationship between air pollutants and COPD, and their respective sample sizes are small, resulting in inconsistent results. The aim of this study is to analyze the effects of air pollutants on COPD hospitalizations in Lanzhou, China. Methods An ecological time series study with distributed lag non-linear model (DLNM) was used for analysis. Daily COPD hospitalization data in Lanzhou from 1 January 2015 to 31 December 2019 were collected from 25 hospitals, as well as air pollutant data and meteorological data. Results A total of 18,275 COPD hospitalizations were enrolled. For 10 μg/m 3 increase in PM 2.5 , PM 10 , SO 2 , NO 2 , and 1 mg/m 3 increase in CO at lag 07 day, the RR95%CI of COPD hospitalizations were 1.048 (1.030, 1.067), 1.008 (1.004, 1.013), 1.091 (1.048, 1.135), 1.043 (1.018, 1.068), and 1.160 (1.084, 1.242), respectively. The exposure–response curves between air pollutants (except O3-8h) and COPD hospitalizations were approximately linear with no thresholds. Female, and the harmful effect of PM on aged <65 years, the effect of gaseous pollutant on those aged ≥65 years, were stronger, particularly in the cold season. Exposure to air pollutants (except O 3-8h ) might increase the risk of COPD hospitalizations. O 3-8h has a weak and unstable effect on COPD. Conclusion Exposure to air pollutants (except O 3-8h ) increases the risk of COPD hospitalizations. O 3-8h has a weak and unstable effect on COPD hospital admissions. The harmful effect of gaseous pollutants (except O 3-8h ) on COPD-hospitalized patients was stronger than that of PM

Air pollutants · Air pollution · China · COPD · Distributed lag · Environmental health · Geography · Pollutant · Air Quality and Health Impacts · Chemistry · Chronic Obstructive Pulmonary Disease (COPD) Research · Environmental Science · Indoor Air Quality and Microbial Exposure · Mathematics · Medicine · Internal Medicine

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