Meta-analysis of the effects of physical activity on ocular biometrics in children and adolescents
Bibliographic Data
| ID | 22083202 |
|---|---|
| Authors | Pengfei Nie (Kunsan National University), Tong Feng (0009-0004-5022-8422, Kunsan National University, corresponding author) |
| Year | 2025 |
| Volume | 13 |
| Pages | 1615033-1615033 |
| Publication date | 2025-06-11 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2025.1615033 |
| PMID | 40567953 |
| OpenAlex | W4411221901 |
| Language | EN |
| Citations received | 1 |
| References cited | 57 |
Introduction Physical activity is recognized as an effective strategy for preventing myopia and cardiovascular diseases in children and adolescents; however, its impact on ocular biological parameters in this population remains poorly understood. This study systematically evaluates the effects of physical activity on ocular parameters in children and adolescents, aiming to provide a theoretical foundation for myopia and cardiovascular disease prevention. Methods The study was registered on PROSPERO (CRD4202454649). A comprehensive search of electronic databases—Web of Science, Embase, Cochrane Library, and PubMed—was conducted from their inception through April 2025. Two reviewers independently performed literature screening, data extraction, and risk-of-bias assessments using predefined inclusion/exclusion criteria. Methodological quality was evaluated using the PEDro and NOS scales, and outcomes were analyzed via network meta-analysis in RevMan 5.3. Results Fourteen studies [8 randomized controlled trials (RCTs), 3 cross-sectional studies, 2 non-randomized controlled trials (NRCTs), and 1 cohort study] involving 12,548 participants aged 6–26 years were included. Meta-analysis revealed that physical activity significantly improved KVA (MD = 0.23, 95% CI = 0.18–0.29, p < 0.001), enhanced UDVA (MD = 0.2, 95% CI = 0.08–0.32, p < 0.001), delayed axial length (AL) progression (MD = 0.2, 95% CI = 0.08–0.32, p < 0.001), suppressed spherical equivalent refraction (SER) progression (MD = 0.2, 95% CI = 0.08–0.32, p < 0.001), reduced central retinal venular equivalent (CRVE) (MD = −2.50, 95% CI = −4.86 to −0.13, p = 0.04), and narrowed central retinal arteriolar equivalent (CRAE) (MD = −2.50, 95% CI = −4.86 to −0.13, p = 0.04). Physical activity demonstrably enhances dynamic and uncorrected distance vision, attenuates SER progression, and positively influences retinal vascular parameters. Conclusion Regular physical activity effectively slows myopia development and progression in children and adolescents while contributing to the prevention of cardiovascular diseases. Systematic review registration https://www.crd.york.ac.uk/PROSPERO/view/CRD42024546449
Biometrics · Computer security · Physical activity · Physical medicine and rehabilitation · Computer Science · Medicine · Ophthalmology and Visual Impairment Studies · Psychology · Retinal Imaging and Analysis · Retinopathy of Prematurity Studies
The Lancet Global Health Commission on Global Eye Health
The Combination of Estimates from Different Experiments
Evidence Based Physical Activity for School-age Youth
Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050
Preferred reporting items for systematic reviews and meta-analyses
The impact of additional visual tasks in physical exercise on balance ability among 9–10-year-old children
Effect of physical activity combined with extra ciliary-muscle training on visual acuity of children aged 10–11
Effects of physical activity combined with different visual target presentation durations of ciliary-muscle training on visual acuity in children
Efficacy of outdoor interventions for myopia in children and adolescents
| Citations per year | 1 |
|---|---|
| Citation span | 2026 - 2026 (1) |
| Highly cited | No |