Global trends in fall-induced hip fractures among perimenopausal women 1990 to 2021
Results from the global burden of disease study 2021
Bibliographic Data
| ID | 22083830 |
|---|---|
| Authors | Zhen Wang (0000-0001-6729-2640, Sichuan University), Zijian Chen (0000-0002-8502-4110, Sichuan University), Chaoyi Zhang (0000-0001-8492-9711, Sichuan University), Wenzheng Liu (0000-0003-0710-5748, Sichuan University), Jin Liu (0000-0001-5816-2422, Sichuan University), Jixi Liu, Wei Lin (0000-0002-5484-0860, Sichuan University, corresponding author), Guanglin Wang (0000-0002-8100-0007, Sichuan University, corresponding author) |
| Year | 2025 |
| Volume | 13 |
| Pages | 1674535-1674535 |
| Publication date | 2025-10-14 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2025.1674535 |
| PMID | 41164841 |
| OpenAlex | W4415172566 |
| Language | EN |
| References cited | 48 |
Background Fall-induced hip fractures in perimenopausal women (FHFPW) are major clinical and public health concern, contributing significantly to global morbidity. This study examines the global impact of FHFPW, focusing on the prevalence, incidence, and years lived with disability (YLDs) across different age groups, regions, and levels of Socio-demographic index (SDI) from 1990 to 2021. The aim is to provide epidemiological data that can inform health policies, and enhance strategies for the prevention and treatment of hip fractures in perimenopausal women. Methods We extracted registered data on incidence cases, prevalence cases, and YLD cases, along with the corresponding rates and their 95% uncertainty intervals (UIs), from the Global Burden of Disease (GBD) 2021 database. All rates in this study were expressed per 100,000 population. The estimated annual percentage change (EAPC) was used to assess changes in the burden of FHFPW and Spearman’s correlation tests were used to examine the relationship between SDI and the burden of FHFPW. The average annual percentage change (AAPC) was further calculated to evaluate temporal trends. Results The disease burden of FHFPW was substantially higher in the 50-54-year age group than in the 45-49-year group. In 2021, there were 300,104 cases among women aged 50–54 years, compared with 164,196 cases in the 45-49-year group. From 1990 to 2021, although the absolute numbers of prevalent cases, incident cases, and YLDs increased, the corresponding incidence, prevalence, and YLDs rates declined. The burden was greater in high-SDI regions, particularly in Oceania, where the prevalence in the 50-54-year group demonstrated the most striking increase (+295.7%). Joinpoint analysis further indicated that, overall, prevalence and YLDs rates showed a downward trend, whereas incidence in the 50-54-year group within high-SDI regions exhibited the most pronounced rise (AAPC = 0.8%; p < 0.001). Conclusion The global burden of disease for FHFPW remains high and tends to increase further; age is an important influencing factor. The burden of disease shows significant regional variations, with a higher burden of disease in regions with high SDI
Burden of disease · Disease · Disease burden · Double burden · Global health · MEDLINE · Bone health and osteoporosis research · Hip and Femur Fractures · Pregnancy-related medical research · Epidemiology
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (Dalys), and healthy life expectancy (Hale) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021
Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019
Seasonally Dependent Change of the Number of Fractures after 50 Years of Age in Poland—Analysis of Combined Health Care and Climate Datasets
| Highly cited | No |
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