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Gonorrhoea among China’s aging population

A 20-year nationwide analysis of epidemiological trends with 5-year projections

Bibliographic Data

ID22084534
AuthorsRui-Rui Peng (0000-0002-2250-8353, Shanghai Skin Disease Hospital), Zuo-Xi Chen (Shanghai Skin Disease Hospital), Juan Wu (0009-0005-7834-8976, Shanghai Skin Disease Hospital), Wu Juan (0000-0001-5525-9026), Mei Shi (0000-0002-7098-6886, Shanghai Skin Disease Hospital), Xin Zheng (0000-0001-9176-8856, Shanghai Skin Disease Hospital), Chun-Jie Liao (Shanghai Skin Disease Hospital), Lin Zhu (0000-0001-5298-7431, Shanghai Skin Disease Hospital), Xiang-Dong Gong (Chinese Academy of Medical Sciences & Peking Union Medical College, corresponding author), Fu-Quan Long, Fuquan Long (0000-0001-7355-503X, Shanghai Skin Disease Hospital, corresponding author)
Year2025
Volume13
Pages1594289-1594289
Publication date2025-06-27
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1594289
PMID40655216
OpenAlexW4411706370
LanguageEN
References cited34

Background: Advances in longevity and pharmacological interventions have facilitated sustained sexual activity among older adults, increasing their vulnerability to sexually transmitted infections. Existing research on older adults in China has largely concentrated on HIV and syphilis, leaving critical gaps in knowledge regarding gonorrhoea. Objectives: We aimed to analyze trends in gonorrhoea incidence among Chinese older adults aged 60 years and above from 2004 to 2023, and to forecast infection trajectories over the next 5 years. Methods: Data were sourced from the National Center for STD Control and the National Bureau of Statistics Yearbooks, standardized and stratified by gender and age groups. Temporal trend analysis utilized Joinpoint regression, and prediction model was developed utilizing an optimized Long Short-Term Memory model. Results: We found: (1) An overall declining yet fluctuating incidence rate (AAPC -5.84; 95% CI, -10.13 to -1.34) with three distinct phases; (2) A consistent predominance of cases among males across all age groups; (3) Slower decline rates in older age groups, particularly among those aged ≥80 years; and (4) A significant reduction in incidence rates during the COVID-19 pandemic. We projected stabilization of overall gonorrhoea incidence rates over the next 5 years (APC -3.22; 95% CI, -6.69 to 0.37), with pronounced upward trend anticipated in the ≥80 age group (APC 20.09; 95% CI, 7.71 to 33.89). Conclusion: The study highlights persistent gonorrhoea transmission risks among older adults in China, particularly the upward trajectory in the ≥80 age group. These findings call for integrating geriatric sexual health education with strengthened monitoring systems to address evolving epidemiological patterns

Age groups · China · Disease · Environmental health · Geography · Pandemic · Population · Population ageing · Psychological intervention · Syphilis · Demography · Medicine · Reproductive tract infections research · Syphilis Diagnosis and Treatment · Virology and Viral Diseases · Epidemiology · Gerontology · Immunology

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    Open Access•Xinxin Chen, John Giles et al.•The Lancet•2022

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    Open Access•Zhixin Zhu, Xiaoxia Zhu et al.•Frontiers in Public Health•2022

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