Associations between maternal exposure to ambient air pollution and very low birth weight

A birth cohort study in Chongqing, China

Bibliographic Data

ID22084718
AuthorsWenzheng Zhou (0000-0002-7167-3320, Chongqing Maternal and Child Health Hospital), Xin Ming (0000-0002-0289-8438, Chongqing Maternal and Child Health Hospital), Yunping Yang (0000-0003-4151-1264, Chongqing Maternal and Child Health Hospital), Yaqiong Hu (0000-0002-7062-0374, Chongqing Maternal and Child Health Hospital), Ziyi He (0009-0008-7068-0773, Chongqing Maternal and Child Health Hospital), Hongyan Chen (0000-0001-9447-5434, Chongqing Maternal and Child Health Hospital), Yannan Li (0000-0001-5298-1742, Chongqing Maternal and Child Health Hospital), Cheng Jin (0000-0002-0903-1685, Army Medical University, corresponding author), Jin Cheng (0000-0003-2535-4422), Xiaojun Zhou (0000-0003-2565-1398, Chongqing Maternal and Child Health Hospital, corresponding author)
Year2023
Volume11
Pages1123594-1123594
Publication date2023-03-07
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1123594
PMID36960371
OpenAlexW4323364392
LanguageEN
Citations received2
References cited37

Introduction There have been many researches done on the association between maternal exposure to ambient air pollution and adverse pregnancy outcomes, but few studies related to very low birth weight (VLBW). This study thus explores the association between maternal exposure to ambient air pollutants and the risk of VLBW, and estimates the sensitive exposure time window. Methods A retrospective cohort study analyzed in Chongqing, China, during 2015–2020. The Generalized Additive Model were applied to estimate exposures for each participant during each trimester and the entire pregnancy period. Results For each 10 μg/m 3 increase in PM 2.5 during pregnancy, the relative risk of VLBW increased on the first trimester, with RR = 1.100 (95% CI: 1.012, 1.195) in the single-pollutant model. Similarly, for each 10 μg/m 3 increase in PM 10 , there was a 12.9% (RR = 1.129, 95% CI: 1.055, 1.209) increase for VLBW on the first trimester in the single-pollutant model, and an 11.5% (RR = 1.115, 95% CI: 1.024, 1.213) increase in the multi-pollutant model, respectively. The first and second trimester exposures of NO 2 were found to have statistically significant RR values for VLBW. The RR values on the first trimester were 1.131 (95% CI: 1.037, 1.233) and 1.112 (95% CI: 1.015, 1.218) in the single-pollutant model and multi-pollutant model, respectively; The RR values on the second trimester were 1.129 (95% CI: 1.027, 1.241) and 1.146 (95% CI: 1.038, 1.265) in the single-pollutant model and multi-pollutant model, respectively. The RR of O3 exposure for VLBW on the entire trimester was 1.076 (95% CI: 1.010–1.146), and on the second trimester was 1.078 (95% CI: 1:016, 1.144) in the single-pollutant model. Conclusion This study indicates that maternal exposure to high levels of PM 2.5 , PM 10 , NO 2 , and O 3 during pregnancy may increase the risk of very low birth weight, especially for exposure on the first and second trimester. Reducing the risk of early maternal exposure to ambient air pollution is thus necessary for pregnant women

Air pollution · Biology · Birth weight · China · Cohort · Cohort study · Environmental health · Geography · Low birth weight · Pregnancy · Air Quality and Health Impacts · Demography · Energy and Environment Impacts · Health, Environment, Cognitive Aging · Medicine · Pediatrics

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