Objective physical activity characteristics and long-term functional disability trajectories in community-dwelling older adults
The amplifying risk of stroke
Bibliographic Data
| ID | 22085044 |
|---|---|
| Authors | Jianhui Pan (Southern Medical University), Zanzhi Wang (Southern Medical University), Yaoquan He (Southern Medical University), Shuang Liu (0000-0002-8749-3607, Southern Medical University), Kao Zhang (Southern Medical University), Jinliang Peng (Ganzhou People's Hospital), Chun Xu (0000-0001-7893-6341, Southern Medical University), Jun Zhang (0000-0003-1706-1611, Ganzhou People's Hospital, corresponding author), Peng Huang (0000-0001-5614-786X, Ganzhou People's Hospital, corresponding author) |
| Year | 2026 |
| Volume | 14 |
| Pages | 1792601-1792601 |
| Publication date | 2026-04-07 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2026.1792601 |
| PMID | 42022829 |
| OpenAlex | W7151264554 |
| Language | EN |
| References cited | 37 |
Background: Functional decline is a major challenge in aging, particularly for those with a history of cerebrovascular events. Yet, prior research relies heavily on self-reported measures. The impact of objective physical activity patterns, particularly sedentary accumulation, on long-term functional prognosis remains unclear. Methods: = 1.9 million). Group-Based Trajectory Modeling (GBTM) was applied to 7 years of follow-up data to identify trajectories of ADL disability. Wrist-worn accelerometry captured objective activity profiles. Weighted logistic regression and restricted cubic splines assessed associations between activity metrics and adverse trajectories. Results: Three distinct trajectories were identified: "Robust," "Progressive Decline," and "Persistent Severe Disability." Stroke survivors were disproportionately represented in the severe disability group compared to controls (35% vs. 10%). Although stroke survivors constituted a small proportion of the unweighted sample, they exhibited a profoundly amplified vulnerability to sedentary behaviors. Average sedentary bout length emerged as a core risk factor independent of total activity volume (aOR 1.15 per 10-min increase). Total activity exhibited an "L-shaped" protective association, while sedentary time showed a "J-shaped" risk threshold (>700 min/day). Interaction analysis revealed that frequent interruptions of sedentary time could partially offset the risks associated with low total activity volume. Conclusion: Beyond total activity volume, continuous sedentary patterns are critical biomarkers of functional decline in older adults. Stroke survivors represent a highly vulnerable subpopulation where clinical rehabilitation strategies should prioritize 'sedentary interruption'
Activities of daily living · Logistic regression · Physical activity · Sedentary lifestyle · Balance, Gait, and Falls Prevention · Physical Activity and Health · Stroke Rehabilitation and Recovery · Rehabilitation
| Highly cited | No |
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