Epidemiologic characteristics of leprosy in Mainland China, 2004–2020

Bibliographic Data

ID22085161
AuthorsYuanchao Yang (Huizhou Central People's Hospital), Jiaqi Zeng (0009-0002-1738-8948, Jinan University), Jingyi Li (0009-0008-6009-6055, Huizhou Central People's Hospital, corresponding author)
Year2025
Volume13
Pages1666605-1666605
Publication date2025-09-24
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1666605
PMID41069832
OpenAlexW4414483479
LanguageEN
References cited18

Background: . This study aimed to elucidate the epidemiological characteristics of this condition in China from 2004 to 2020. Methods: New leprosy case and incidence data covering all 31 provinces in Mainland China from 2004 to 2020 were collected from the Data Center of China's Public Health Science. The temporal, regional, and age-specific distributions of leprosy were analyzed through epidemiological methods. Results: From 2004 to 2020, a total of 5,478 leprosy cases were reported in China, with an average annual incidence rate of 0.0239 per 100,000 population, which indicates a low and stable endemicity. Geographically, the highest disease burden was observed in Yunnan, Guangdong, Sichuan, Guizhou, and Guangxi provinces. Regarding age distribution, the majority of cases were observed among individuals aged 30-49 years (2,171 cases, 39.63%), and the highest incidence rate was found in the 60-69-year age group. Conclusion: Leprosy incidence remained stably low nationwide and displayed significant regional variation. New cases clustered predominantly in Southwestern and Central-South China (Yunnan, Guangdong, Sichuan, Guizhou, and Guangxi). The disease burden showed distinct age patterns, with the highest case numbers detected in middle-aged adults and peak incidence rates in the older population. Targeted prevention strategies should prioritize these high-burden regions and peak-affected age groups

Disease · Disease burden · Leprosy · Mainland · Mainland China · Dermatological diseases and infestations · Leprosy Research and Treatment · Parasites and Host Interactions · Epidemiology

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Open DOIOpen Access