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Prevalence and associations of adverse childhood experiences with anxiety and depressive symptoms in Indonesia

Bibliographic Data

ID22085624
AuthorsKaren Arulsamy (0000-0002-6135-1598, Duke-NUS Medical School, corresponding author), Elmeida Effendy (0000-0002-9382-3609, Universitas Sumatera Utara), Sarah Mardhiyah, Sarah A Mardhiyah (0000-0002-2268-4218, Universitas Sumatera Utara), Mustafa M Amin (0000-0003-0912-9372, Universitas Sumatera Utara), Muhammad Surya Husada (0000-0001-6214-2838, Universitas Sumatera Utara), Vita Camellia (0000-0001-5774-3276, Universitas Sumatera Utara), Anne‐Claire Stona (0000-0003-0350-0345, SingHealth Duke-NUS Academic Medical Centre), Anne-Claire Stona, Eric A Finkelstein (0000-0001-6443-9686, Duke-NUS Medical School)
Year2025
Volume13
Pages1714676-1714676
Publication date2025-12-10
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1714676
PMID41450489
OpenAlexW4417182060
LanguageEN
References cited67

Background: Research in Southeast Asia-particularly Indonesia-on the link between adverse childhood experiences and adult mental health remains limited. The current study aims to examine the prevalence of ACEs in Indonesia, associations with anxiety and depressive symptoms among adults, and gender differences. Methods: We conducted an online cross-sectional survey of 872 Indonesians aged 21-64 years. ACEs were measured using the WHO ACE-IQ, and anxiety and depressive symptoms with the PHQ-2, GAD-2, and their composite PHQ-4. Associations between ACEs and symptoms were analyzed using weighted regression models adjusting for demographic variables. Results: ACEs were highly prevalent (79.5%), most commonly parental separation (50.9%), emotional neglect (39.4%), and sexual abuse (23.1%). Overall, 38.2% reported one ACE, 22.0% two, and 19.4% three or more. The experience of any ACE is associated with a 0.57-point increase (95% CI = 0.22-0.91) on the GAD-2 and a 0.59-point increase (95% CI = 0.30-0.88) on the PHQ-2. Any ACE is associated with a 10.0 percentage point (95% CI = 0.02, 0.18) increase in the likelihood of reporting at least mild symptoms of anxiety and a 6.6 percentage point (95% CI = 0.01-0.13) increase in the likelihood of reporting at least mild symptoms of depression. These associations are largest for individuals with 3 ACEs or more. Women face a disproportionate burden of ACEs, in terms of prevalence and cumulative exposure, and worse mental health symptoms. Conclusion: In summary, these findings highlight the importance of interventions that consider cumulative ACE exposure and adopt gender-sensitive approaches to reduce long-term mental health consequences

Adverse Childhood Experiences · Adverse effect · Anxiety · Depressive symptoms · Mental health · Psychological intervention · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes · Child Abuse and Trauma · Child and Adolescent Psychosocial and Emotional Development

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