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Covid-19 Vaccination Does Not Affect Reproductive Health Parameters in Men

Bibliographic Data

ID22085661
AuthorsMarco Reschini (0000-0002-9868-3043, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico), Luca Pagliardini (0000-0002-3960-7454, Vita-Salute San Raffaele University), Luca Boeri (0000-0003-0040-784X, University of Milan), Francesca Piazzini (0009-0001-6371-6570, Azienda Ospedaliero-Universitaria Careggi), Verônica Bandini (0009-0007-3206-6388, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico), Gianfranco Fornelli (0009-0007-4281-0617, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico), Carolina Dolci (0000-0002-3108-4169, Vita-Salute San Raffaele University), Greta Chiara Cermisoni (0000-0003-1856-7390, Vita-Salute San Raffaele University), Paola Viganò (0000-0002-5279-109X, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, corresponding author), Edgardo Somigliana (0000-0002-0223-0032, University of Milan), Maria Elisabetta Coccia (0000-0001-5294-129X, Azienda Ospedaliero-Universitaria Careggi), Enrico Papaleo (0000-0003-0281-9143, Vita-Salute San Raffaele University)
Year2022
Volume10
Pages839967-839967
Publication date2022-02-02
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.839967
PMID35186854
OpenAlexW4210629857
LanguageEN
Citations received2
References cited27

With the implementation of COVID-19 vaccine up-take, doubts regarding the impact of immunization on future fertility have begun to emerge. We have examined vaccine safety on male reproductive health. We set up a multicentre (three infertility centers), retrospective study in order to assess semen parameters and fertilization rate of one hundred-six men in a pairwise comparison between the first and second assisted reproduction technology (ART) attempt, performed respectively before and after COVID-19 vaccination. Median time (range) between the first vaccine dose and the second ART cycle was 75 days (39–112). Semen parameters did not change before and after the exposure. Fertilization rate was also similar before and after vaccination. Twenty-five patients (24%) were oligozoospermic before the vaccination while 26 (25%) after the exposure ( P = 0.87). Severe asthenozoospermia were present in 11 patients before as well as after the exposure. No difference was observed even after considering different types of vaccines (mRNA or viral vector). COVID-19 vaccination did not affect sperm quality and fertilization capacity of men undergoing ART treatments and should be considered safe for men's reproductive health

Andrology · Asthenozoospermia · Biology · Environmental health · Fertility · Gynecology · Human fertilization · Immune system · Immunization · In vitro fertilisation · Infertility · Male infertility · Population · Pregnancy · Reproductive health · Semen · Sperm · Vaccination · COVID-19 Impact on Reproduction · Demography · Genital Health and Disease · Medicine · Psychology · Reproductive Health and Technologies · Immunology

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    Open Access•Katarina L Matthes, Mathilde Le Vu et al.•Population Studies•2025

Citations per year0.67
Citation span2023 - 2025 (3)
Highly citedNo

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