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A case of severe leptospirosis with Jarisch–Herxheimer reaction presenting as respiratory failure

Bibliographic Data

ID22086007
AuthorsYunzhen Shi (Wenzhou Medical University), Wanru Guo (0009-0000-3007-5087, First Affiliated Hospital Zhejiang University), Ming Hu (0000-0003-2583-1161, First Affiliated Hospital Zhejiang University), Yuxuan Wang (0000-0001-5549-3584, Wenzhou Medical University), Jingnan Li (0000-0003-4122-6156, Wenzhou Medical University), Wenjuan Hu (0000-0002-6208-7258, First Affiliated Hospital Zhejiang University), Xiaomeng Li (0000-0002-0727-1263, First Affiliated Hospital Zhejiang University), Kaijin Xu (0000-0001-8126-5008, First Affiliated Hospital Zhejiang University, corresponding author)
Year2023
Volume11
Pages1125306-1125306
Publication date2023-02-10
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2023.1125306
PMID36844847
OpenAlexW4319984906
LanguageEN
References cited12

Background: spp. The treatment of penicillin or tetracycline can cause a Jarisch-Herxheimer reaction (JHR), which can lead to acute respiratory distress syndrome (ARDS) and multi-organ failure in severe cases. The overall course of evolution and imaging features of a JHR exacerbation of leptospirosis have rarely been reported. Case presentation: We present a case of leptospirosis complicated by pulmonary alveolar hemorrhage and a Jarisch-Herxheimer reaction (JHR) that required respiratory and vasopressor support. This case demonstrates a well-defined course of evolution of JHR and the imaging features. Conclusions: Leptospirosis is easily misdiagnosed in some sporadic areas, and JHR complicates its management. Early diagnosis and appropriate treatment can reduce the mortality of severe leptospirosis with JHR

Intensive care medicine · Leptospirosis · Pathology · Respiratory failure · Respiratory system · Leprosy Research and Treatment · Leptospirosis research and findings · Lymphadenopathy Diagnosis and Analysis · Medicine · Internal Medicine

Highly citedNo

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