Lipoprotein(a) in Cardiovascular Diseases
Insight From a Bibliometric Study
Bibliographic Data
| ID | 22088273 |
|---|---|
| Authors | David Šuran (0000-0002-4073-9286, University of Maribor, corresponding author), Helena Blažun Vošner (0000-0003-1998-7346, Alma Mater Europaea), Jernej Završnik (0000-0002-5023-0483, Alma Mater Europaea), Peter Kokol (0000-0001-9102-9359, University of Maribor), Andreja Sinkovič (0000-0001-9887-6841, University of Maribor), Vojko Kanič (0000-0001-9239-2133, University of Maribor), Marko Kokol (0000-0003-4292-989X, University of Maribor), Franjo Naji (0000-0002-1425-4189, University of Maribor), Tadej Završnik (University of Maribor) |
| Year | 2022 |
| Volume | 10 |
| Pages | 923797-923797 |
| Publication date | 2022-07-05 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2022.923797 |
| PMID | 35865239 |
| OpenAlex | W4283822670 |
| Language | EN |
| References cited | 88 |
Lipoprotein(a) [Lp(a)] is a complex polymorphic lipoprotein comprised of a low-density lipoprotein particle with one molecule of apolipoprotein B100 and an additional apolipoprotein(a) connected through a disulfide bond. The serum concentration is mostly genetically determined and only modestly influenced by diet and other lifestyle modifications. In recent years it has garnered increasing attention due to its causal role in pre-mature atherosclerotic cardiovascular disease and calcific aortic valve stenosis, while novel effective therapeutic options are emerging [apolipoprotein(a) antisense oligonucleotides and ribonucleic acid interference therapy]. Bibliometric descriptive analysis and mapping of the research literature were made using Scopus built-in services. We focused on the distribution of documents, literature production dynamics, most prolific source titles, institutions, and countries. Additionally, we identified historical and influential papers using Reference Publication Year Spectrography (RPYS) and the CRExplorer software. An analysis of author keywords showed that Lp(a) was most intensively studied regarding inflammation, atherosclerosis, cardiovascular risk assessment, treatment options, and hormonal changes in post-menopausal women. The results provide a comprehensive view of the current Lp(a)-related literature with a specific interest in its role in calcific aortic valve stenosis and potential emerging pharmacological interventions. It will help the reader understand broader aspects of Lp(a) research and its translation into clinical practice
Apolipoprotein B · Bioinformatics · Biology · Cholesterol · Disease · Lipoprotein · Stenosis · Aortic Thrombus and Embolism · Atherosclerosis and Cardiovascular Diseases · Lipoproteins and Cardiovascular Health · Medicine · Internal Medicine
| Citation velocity | historical |
|---|---|
| Highly cited | No |