Impact of the Covid-19 pandemic on the prevalence of respiratory viral pathogens in patients with acute respiratory infection in Shanghai, China

Bibliographic Data

ID22088776
AuthorsLifeng Pan (0000-0001-9482-3275, Chinese Center For Disease Control and Prevention, corresponding author), Yuan Yang (0000-0002-3030-5476, Shanghai Municipal Center For Disease Control Prevention), Yang Yuan (0000-0003-4193-9439), Qiqi Cui (Chinese Center For Disease Control and Prevention), Xuechun Zhang (0000-0002-2034-210X, Shanghai Municipal Center For Disease Control Prevention), Yujia Huo (0000-0002-4484-7700, Shanghai Municipal Center For Disease Control Prevention), Qing Liu (0000-0002-5792-6037, Shanghai Municipal Center For Disease Control Prevention), Wenwei Zou (Shanghai Municipal Center For Disease Control Prevention), Bing Zhao (0000-0001-5714-3756, Chinese Center For Disease Control and Prevention), Lipeng Hao (Chinese Center For Disease Control and Prevention, corresponding author)
Year2024
Volume12
Pages1230139-1230139
Publication date2024-02-07
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2024.1230139
PMID38384888
OpenAlexW4391602666
LanguageEN
Citations received1
References cited30

Objective: This study aimed to evaluate the impact of nonpharmaceutical interventions (NPIs) taken to combat COVID-19 on the prevalence of respiratory viruses (RVs) of acute respiratory infections (ARIs) in Shanghai. Methods: Samples from ARI patients were collected and screened for 17 respiratory viral pathogens using TagMan low density microfluidic chip technology in Shanghai from January 2019 to December 2020. Pathogen data were analyzed to assess changes in acute respiratory infections between 2019 and 2020. Results: A total of 2,744 patients were enrolled, including 1,710 and 1,034 in 2019 and 2020, respectively. The total detection rate of RVs decreased by 149.74% in 2020. However, detection rates for human respiratory syncytial virus B (RSVB), human coronavirus 229E (HCoV229E), human coronavirus NL63 (HCoVNL63), and human parainfluenza virus 3 (HPIV3) increased by 91.89, 58.33, 44.68 and 24.29%, in 2020. The increased positive rates of RSVB, HPIV3, resulted in more outpatients in 2020 than in 2019. IFV detection rates declined dramatically across gender, age groups, and seasons in 2020. Conclusion: NPIs taken to eliminate COVID-19 had an impact on the prevalence of respiratory viral pathogens, especially the IFVs in the early phases of the pandemic. Partial respiratory viruses resurged with the lifting of NPIs, leading to an increase in ARIs infection

Coronavirus · Disease · Pandemic · Respiratory infection · Respiratory system · Virus · COVID-19 Clinical Research Studies · Infection Control and Ventilation · Medicine · Respiratory viral infections research · Immunology · Internal Medicine · Virology

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