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The Relationship Between Sleep Duration and Blood Lipids Among Chinese Middle-Aged and Older Adults

Cross-Lagged Path Analysis From CHARLS

Bibliographic Data

ID22088902
AuthorsZiwei Chen (0000-0001-8295-7444, Huazhong University of Science and Technology), Xia Zhang (0000-0002-7344-9808, First People's Hospital of Jingzhou), Yanran Duan (0009-0009-8744-7641, Huazhong University of Science and Technology), Tingting Mo (0000-0002-2852-0193, Huazhong University of Science and Technology), Wenli Liu (0000-0003-3254-4363, East China Normal University), Yilei Ma (0009-0009-3401-1561, Huazhong University of Science and Technology, corresponding author), Ping Yin (0000-0002-6818-1552, Huazhong University of Science and Technology, corresponding author)
Year2022
Volume10
Pages868059-868059
Publication date2022-05-13
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.868059
PMID35646780
OpenAlexW4280491251
LanguageEN
Citations received2
References cited42

This study used data from the China Health and Retirement Longitudinal Study to investigate the temporal relationship between blood lipids and sleep duration in Chinese middle-aged and older adults. We used medical examinations and questionnaire data of 5,016 Chinese middle-aged and older adults (age 45+) in 2011 and 2015. Cross-lagged path analysis was performed to examine the bidirectional relationships between blood lipids and sleep duration. Sleep duration and lipids data were analyzed as continuous variables. Temporal relationships between sleep duration and HDL-cholesterol, LDL-cholesterol, total cholesterol, and triglycerides were different. Sleep duration was negatively associated with HDL-cholesterol 4 year later (β 1 = −0.171, P = 0.005), and HDL-cholesterol was negatively associated with sleep duration 4 year later (β 2 = −0.006, P = 0.002). Longer sleep duration was associated lower levels of LDL-cholesterol (β 1 = −0.275, P = 0.097) and total cholesterol (β 1 = −0.329, P = 0.096) 4 year later. There was a positive correlation between triglycerides and sleep duration. The path coefficient from triglycerides to sleep duration 4 year later (β 2 = 0.001, P = 0.018) was greater than that from sleep duration to triglycerides 4 year later (β 1 = 0.109, P = 0.847), with P = 0.030 for the difference between β 1 and β 2 . In stratified analysis, we found that the strength and direction of the relationships may be related to age and BMI. Effects of sleep duration on blood lipids were only observed among participants aged 25

Analysis of variance · Blood lipids · Cholesterol · Cross-sectional study · High cholesterol · Longitudinal study · Medicine · Obesity, Physical Activity, Diet · Sleep and related disorders · Sleep and Work-Related Fatigue · Endocrinology · Internal Medicine

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Unique citing works2
Citations per year2
Citation span2025 - 2025 (1)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 2

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