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Effect of tele-rehabilitation guided intervention on pain and function in middle-aged and older adult patients with knee osteoarthritis

A systematic review and meta-analysis

Bibliographic Data

ID22089075
AuthorsQiqi Jia (0000-0003-4946-1353, Wuhan Sports University), Zhenya Guo, Zhiliang Guo (0000-0002-9956-1945, Henan Polytechnic University), Boyuan Zhang (0009-0006-4855-1655, Wuhan University), Hong Wang (0000-0003-2405-7311, Wuhan Sports University, corresponding author)
Year2025
Volume13
Pages1724092-1724092
Publication date2025-12-17
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2025.1724092
PMID41480085
OpenAlexW4417415174
LanguageEN
References cited59

Objective: To assess the effect of tele-rehabilitation interventions on pain and function in middle-aged and older adult patients with knee osteoarthritis (KOA). Methods: A systematic search of randomized controlled trials (RCTs) was conducted in the EMBASE, PubMed, Cochrane Library, and Web of Science databases, covering the period from 2006 to 31 August 2025. Screening criteria were developed based on the PICOS principle. The Cochrane Risk of Bias Assessment Tool (RoB 2) was used to evaluate the quality of the literature, and meta-analysis was performed using STATA 15.0 software. Results: A total of 12 RCTs involving 1,151 patients were included. The results showed that tele-rehabilitation was effective in VAS Pain (SMD = -0.57, 95% CI: -1.25-0.10), WOMAC pain (SMD = -0.08, 95% CI: -0.98-0.83), WOMAC function (SMD = -0.44, 95% CI: -0.88-0.00), and KOOS total (SMD = 0.52, 95% CI: -0.37-1.40), showing a trend toward improvement, but none reached statistical significance except for WOMAC function score. Sensitivity analyses showed robust results, and Egger's test did not reveal significant publication bias. Conclusion: Tele-rehabilitation shows positive trends in pain and functional improvement in middle-aged and older adult patients with KOA; however, current evidence is insufficient to demonstrate significant superiority. Given its good accessibility, tele-rehabilitation can be used as a complementary modality to traditional rehabilitation. More high-quality studies are needed to clarify its optimal intervention protocol and long-term efficacy. Systematic review registration: PROSPERO (registration number: CRD420251137582)

Activities of daily living · MEDLINE · Osteoarthritis · Randomized controlled trial · Osteoarthritis Treatment and Mechanisms · Telemedicine and Telehealth Implementation · Total Knee Arthroplasty Outcomes

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Highly citedNo
Open DOIOpen Access
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