Risk of ozone exposure-induced fracture
Bibliographic Data
| ID | 22089134 |
|---|---|
| Authors | Shuai Lu (0000-0001-9489-0611, Peking University), Rongrong Xu (0000-0003-3390-2660, Nanjing Medical University), Maoqi Gong (0009-0008-1699-4835, Peking University), Yejun Zha (0000-0001-7124-2128, Peking University), Ning Li (0000-0003-4098-1838, Peking University), Jia Chen (0000-0002-6350-6610, Peking University), Xuejiao Liu (0009-0005-7045-6323, Peking University), Xieyuan Jiang (0000-0002-2993-1357, Peking University, corresponding author) |
| Year | 2023 |
| Volume | 11 |
| Pages | 1153256-1153256 |
| Publication date | 2023-03-16 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2023.1153256 |
| PMID | 37006579 |
| OpenAlex | W4327618031 |
| Language | EN |
| Citations received | 1 |
| References cited | 34 |
Introduction Ozone (O 3 ) is known to induce oxidative stress that influences various cells and tissues, which may further lead to diminished bone mineral density. Nevertheless, few studies have investigated the association between O 3 exposure and fractures. Considering the similar growing trends of O 3 concentrations and fracture morbidity in recent years, in the present study, we aimed to examine whether O 3 exposure is associated with the fracture morbidity. Methods Using a retrospective cohort study design, we analyzed the records of 8,075 patients with fracture admitted in the warm season to Beijing Jishuitan Hospital from 2014 to 2019 and matched them to the corresponding exposure time and concentration of O 3 . Results The results showed that increased odds of fracture were associated with increased O 3 concentrations, presumably because O 3 induces oxidative stress (OS) that leads to bone mineral density (BMD) loss. Discussion Our findings suggest that O 3 exposure is a risk factor for fractures, providing new evidence of the adverse health effect induced by air pollution. We can conclude that more intensive air pollution control is needed for the prevention of fracture occurrence
Air pollution · Beijing · Biology · Bone mineral · China · Environmental health · Odds ratio · Osteoporosis · Oxidative stress · Ozone · Retrospective cohort study · Risk factor · Air Quality and Health Impacts · Chemistry · Climate Change and Health Impacts · Medicine · Radiation Dose and Imaging · Internal Medicine
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2025 - 2025 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |