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Risk Diagrams Based on Primary Care Electronic Medical Records and Linked Real-Time PCR Data to Monitor Local Covid-19 Outbreaks During the Summer 2020

A Prospective Study Including 7,671,862 People in Catalonia

Bibliographic Data

ID22089477
AuthorsMartí Català (0000-0003-3308-9905, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol), Ermengol Coma (0000-0001-8000-3321, Institut Català de la Salut), Sergio Alonso (0000-0001-6620-328X, Universitat Politècnica de Catalunya), Enrique Alvarez-Lacalle (0000-0001-6824-6857, Universitat Politècnica de Catalunya), Silvia Cordomi (Institut Català de la Salut), Daniel López (0000-0003-2652-5959, Universitat Politècnica de Catalunya), Daniel López-Codina (0000-0002-0408-4526, Universitat Politècnica de Catalunya), Francesc Fina (0000-0001-7106-5635, Institut Català de la Salut), Manuel Medina (0000-0001-9618-3822, Institut Català de la Salut), Manuel Medina-Peralta, Clara Prats (0000-0002-1398-7559, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, corresponding author), Daniel Prieto-Alhambra, Daniel Prieto‐Alhambra (0000-0002-3950-6346, Office for National Statistics)
Year2021
Volume9
Pages693956-693956
Publication date2021-07-05
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2021.693956
PMID34291033
OpenAlexW3184654165
LanguageEN
Citations received4
References cited14

Monitoring transmission is a prerequisite for containing COVID-19. We report on effective potential growth (EPG) as a novel measure for the early identification of local outbreaks based on primary care electronic medical records (EMR) and PCR-confirmed cases. Secondly, we studied whether increasing EPG precedes local hospital and intensive care (ICU) admissions and mortality. Population-based cohort including all Catalan citizens' PCR tests, hospitalization, intensive care (ICU) and mortality between 1/07/2020 and 13/09/2020; linked EMR covering 88.6% of the Catalan population was obtained. Nursing home residents were excluded. COVID-19 counts were ascertained based on EMR and PCRs separately. Weekly empirical propagation (ρ 7 ) and 14-day cumulative incidence (A 14 ) and 95% confidence intervals were estimated at care management area (CMA) level, and combined as EPG = ρ 7 × A 14 . Overall, 7,607,201 and 6,798,994 people in 43 CMAs were included for PCR and EMR measures, respectively. A14, ρ 7 , and EPG increased in numerous CMAs during summer 2020. EMR identified 2.70-fold more cases than PCRs, with similar trends, a median (interquartile range) 2 (1) days earlier, and better precision. Upticks in EPG preceded increases in local hospital admissions, ICU occupancy, and mortality. Increasing EPG identified localized outbreaks in Catalonia, and preceded local hospital and ICU admissions and subsequent mortality. EMRs provided similar estimates to PCR, but some days earlier and with better precision. EPG is a useful tool for the monitoring of community transmission and for the early identification of COVID-19 local outbreaks

Environmental health · Intensive care · Intensive care medicine · Intensive care unit · Interquartile range · Medical record · Outbreak · Population · COVID-19 Clinical Research Studies · COVID-19 epidemiological studies · Data-Driven Disease Surveillance · Medicine · Emergency Medicine · Internal Medicine · Virology

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Unique citing works4
Citations per year1
Citation span2022 - 2024 (3)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 4

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