Associations between psycho-behavioral risk factors and diabetic retinopathy

Nhanes (2005–2018)

Bibliographic Data

ID22090483
AuthorsXiaojia Sun (Xijing Hospital), Xiao-Jia Sun, Guo-Heng Zhang (Xijing Hospital), Changmei Guo (0000-0002-1659-4451, Xijing Hospital), Chang-Mei Guo, Ziyi Zhou (0000-0002-9775-3839, Xijing Hospital), Zi-Yi Zhou, Ya-Li Niu, Yali Niu (Xijing Hospital), Ling Wang (0000-0002-5015-7706, Air Force Medical University, corresponding author), Guo‐Rui Dou (0000-0002-3107-1835, Xijing Hospital, corresponding author), Guo-Rui Dou
Year2022
Volume10
Pages966714-966714
Publication date2022-09-15
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2022.966714
PMID36187629
OpenAlexW4296094950
LanguageEN
Citations received3
References cited44

Introduction Diabetes mellitus (DM) and diabetic retinopathy (DR) increase the global burden. Since their pathogenesis is complex, it is necessary to use the biopsychosocial model to discover the most effective strategies. The study is aimed to investigate the psycho-behavioral factors of DR and confirm the discrepancies from previous studies. Research design and methods The study comprised seven cycles of cross-sectional data of the National Health and Nutrition Examination Survey (NHANES) from 2005–2006 to 2017–2018. Samples of DM were selected from this complex multi-stage probability sample and divided into the non-DR and DR groups, where 4,426 samples represented 18,990,825 individuals after weighting. This study comprehensively explored the biological, social, and psychological risk factors of DR, among which the biological factors included blood pressure, blood routine, HbA1c%, blood glucose, the duration of DM, family history, comorbidities, and treatment methods. Social aspects include gender, education, income, insurance, smoking, drinking, sleep habits, and recreational activities. The Patient Health Questionnaire-9 (PHQ-9) was used to assess the psychological state. Taylor series regression was used to examine the connection between factors and DR. Results Men accounted for 55.5% of the DR group ( P = 0.0174). Lymphocyte count, insulin treatment, heart failure, stroke, liver condition, and renal failure showed significant differences in DR ( P 0.05). Conclusions The biological risk factors of DR are significant. It showed that stroke is associated with DR, and retinal exams have the potential value as a screening tool for the brain. Besides, psycho-behavioral risk factors of DR should also be paid attention. Our study highlights that mild and moderate depression and ≤6 h of sleep are distinguishably associated with DM complicated with DR. It indicates that psycho-behavioral risk factors confer a vital influence on diabetic health care and DR

Confidence interval · Diabetes mellitus · Environmental health · National Health and Nutrition Examination Survey · Odds ratio · Population · Diabetes Management and Education · Diabetes, Cardiovascular Risks, and Lipoproteins · Medicine · Retinal Diseases and Treatments · Endocrinology · Gerontology · Internal Medicine

Tools

Open DOIOpen Access