Positive Effect of Fermented Camel Milk on Liver Enzymes of Adolescents with Metabolic Syndrome
A Double Blind, Randomized, Cross-over Trial
Bibliographic Data
| ID | 22320328 |
|---|---|
| Authors | Zahra Fallah (0000-0001-7914-0492, Child Development Center), Awat Feizi (0000-0002-1930-0340, Isfahan University of Medical Sciences), Mahin Hashemipour (Development Research Center), Roya Kelishadi (0000-0001-7455-1495, Isfahan University of Medical Sciences, corresponding author) |
| Year | 2018 |
| Volume | 30 |
| Issue | 1 |
| Pages | 20 |
| Publication date | 2018-01-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Materia Socio Medica (JOURNAL) |
| Journal identifiers | ISSN: 1512-7680 • E-ISSN: 1986-597X |
| Publisher | ScopeMed (PUBLISHER • TR) |
| DOI | 10.5455/msm.2018.30.20-25 |
| PMID | 29670474 |
| OpenAlex | W2793978321 |
| Language | EN |
| References cited | 2 |
BACKGROUND: Metabolic syndrome (MetS) has several health consequences. Liver enzymes elevation is among them. AIM: This study aimed to assess the effects of fermented Camel milk (FCM), as a functional food and dairy, on some features of MetS in adolescents including liver enzymes status, serum lipids and anthropometric measures. METHODS: Overweight/obese adolescents with MetS were randomly assigned to FCM 250 cc per day for 8 weeks, a 4-week washout, and then to diluted Cow's yogurt (DCY) 250 cc per day for 8 weeks, or the reverse sequence. Anthropometric measures, liver enzymes and serum lipids were measured just before and after each one of the four periods. A three-day food record and physical activity questionnaire were completed before each period. Statistical analyses were done using Minitab and SPSS soft-wares considering the significance level of 0.05. RESULTS: Twenty-four participants with a mean age (SD) of 13.77 (1.87) years (range: 10.45-16.25) (58% girls) completed the study. It resulted significant mean reduction of aspartate aminotransferase (AST) (-3.75 U/L [95% CI: -7.06; -0.43]; p=0.042) and alanine aminotransferase (ALT) (-2.54 U/L [95% CI: -3.33; -2.24], and p=0.006) and AST/ALT ratio (-0.16 U/L [95% CI: -0.28; -0.05]; p= 0.029) by FCM consumption in comparison to DCY. Non-significant favorable effects on anthropometric measures and serum lipids were seen as well. CONCLUSION: According to the observed favorable effects of fermented camel milk on liver enzymes, its consumption may be considered as a functional food supplement in related circumstances
Alanine aminotransferase · Animal science · Anthropometry · Biology · Camel milk · Elevated liver enzymes · Liver enzyme · Metabolic syndrome · Obesity · Overweight · Statistical significance · Animal Diversity and Health Studies · Infant Nutrition and Health · Medicine · Veterinary Equine Medical Research · Food Science · Gastroenterology · Internal Medicine
| Highly cited | No |
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