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Changing Discourse on In Vitro Gametogenesis

Expectation, Scientific Reality, and the Ethics of Hype

Bibliographic Data

ID22421634
AuthorsDaisuke Yamashita (Kyoto University), Yusuke Shikano (Issues Research), Katsuhiko Hayashi (Osaka Gakuin University), Mitinori Saitou (Kyoto University), Misao Fujita (0000-0001-7919-5362, Kyoto University), Minoru Irahara (Tokushima University), Moeko Isono (Ethics and Public Policy Center), Tadashi Kimura (0000-0003-1279-9078, Sakai Municipal Hospital), Atsushi Kogetsu (0000-0002-0465-8163, Kyoto University), Takehiko Ogawa (Yokohama City University), Reina Ozeki-Hayashi (0000-0002-4394-7830, Tohoku University), Kazuto Kato (The University of Osaka, corresponding author)
Year2026
Publication date2026-06-05
Open AccessYes
TypeARTICLE
VenueMonash Bioethics Review (JOURNAL)
Journal identifiersISSN: 1321-2753 • E-ISSN: 1836-6716
PublisherSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1007/s40592-026-00295-0
PMID42247096
OpenAlexW7163657373
LanguageEN
References cited10

In vitro gametogenesis (IVG) has attracted growing attention as a transformative reproductive technology, despite its remaining largely at the stage of basic research. This paper analyzes how IVG is represented across academic and media discourse, with a particular focus on expectations surrounding its clinical applications and the ethical implications of such expectations. Drawing on a qualitative review of bioethical literature, selected media reports, and discussions with IVG researchers, the study identifies a shared tendency to frame IVG in terms of its potential use in human reproduction, often presuming near-term feasibility. This forward-looking framing contrasts with the current scientific reality, in which significant technical and safety challenges remain unresolved. The paper argues that this discrepancy contributes to a form of “hype,” wherein speculative applications prematurely shape public understanding and ethical debate. Such hype may distort discussions on ethics and policy, amplify unrealistic expectations, and obscure the value of basic research. By clarifying the gap between scientific practice and societal perception, this study highlights the need for responsible communication and ethically grounded discourse. It concludes that fostering accurate public understanding is essential for the governance of emerging biotechnologies such as IVG.

Bioethics · Corporate governance · Ethical issues · Public discourse · Qualitative research · Science communication · Technoscience · Transformative learning · Prenatal Screening and Diagnostics · Reproductive Biology and Fertility · Reproductive Health and Technologies

Highly citedNo

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Open DOIOpen Access
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