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Artificial intelligence in medical ethics education

A descriptive study of eight models in multiple choice question generation

Bibliographic Data

ID22425141
AuthorsJohn Obeid (Central Michigan University), Chris Bobier (0000-0003-4194-4721, Central Michigan University, corresponding author), Christopher Bobier, Alex R Gillham (0000-0003-2234-6945, St. Bonaventure University), Alex Gillham, Adam Omelianchuk (0000-0003-3241-2870, Baylor College of Medicine), Daniel J Hurst (0000-0003-0592-2592, Stratford University), Daniel Hurst
Year2026
Volume26
Issue1
Publication date2026-02-07
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueBMC Medical Education (JOURNAL)
Journal identifiersISSN: 1472-6920 • E-ISSN: 1472-6920
PublisherSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1186/s12909-026-08781-z
PMID41654925
OpenAlexW7128295288
LanguageEN
Citations received1
References cited21

INTRODUCTION: Integrating artificial intelligence (AI) into medical education poses barriers and opportunities for medical educators. One of those opportunities is content creation for medical ethics assessment. Assessing the performance of AI in generating multiple choice questions (MCQs) in ethics that aligns with United States Medical Licensing Examination (USMLE) is important. The present study evaluates the performance of eight AI models-GPT-4 Turbo, GPT-3.5 Turbo 0125, o1 Mini, o1 Preview, GPT-4, Claude 3.5 Sonnet, Claude 3 Opus, and Gemini-in regard to the relevance, clarity, and accuracy of generated ethics-based MCQs. METHODS: Each of the eight models was tasked with generating two sets of question, answer, and explanation for each of 13 selected USMLE-aligned student learning outcomes related to medical ethics. Responses were rated by four independent experts in medical ethics on relevance, clarity, and accuracy. Performance metrics were assessed using mean, median, range, and total scores, with an overall percentage score computed for each model. Qualitative responses noting strengths and weaknesses were collected. RESULTS: Claude 3.5 Sonnet had the highest overall performance (86.28%), accuracy (85.57%), and clarity (91.73%). o1 Mini followed closely with an overall score of 85.19%, while GPT-4 had the highest rating for relevance (88.65%) and a total score of 84.87%. GPT-4 Turbo and o1 Preview had the lowest overall score at 76.79%. Identified weaknesses included incorrect answer selection, best answer not available, and the question was not ethics-based. CONCLUSION: The findings indicate clear potential for medical educators tasked with designing medical ethics MCQs for teaching and assessment. However, expert oversight is needed to ensure proper utilization. DATA AVAILABILITY STATEMENT: Data supporting the findings of this study are available from the corresponding author on request.

Descriptive research · Descriptive statistics · Medical ethics · Medical research · Multiple choice · Research ethics · AI in Service Interactions · Artificial Intelligence in Healthcare and Education · Clinical Reasoning and Diagnostic Skills

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Unique citing works1
Citations per year1
Citation span2026 - 2026 (1)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 1

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