Erosive peripheral polyarthritis in ancient Japanese skeletons
A possible case of rheumatoid arthritis
Bibliographic Data
| ID | 22475176 |
|---|---|
| Authors | Koji Inoue (0000-0001-9817-150X, Shiga University of Medical Science, corresponding author), Sinsuke Hukuda (Shiga University of Medical Science), Masashi Nakai (0000-0002-1219-9307, Kyoto University), Kazumichi Katayama (Kyoto University), Jie Huang (0009-0007-4279-2914, Shiga University of Medical Science) |
| Year | 1999 |
| Volume | 9 |
| Issue | 1 |
| Pages | 1-7 |
| Publication date | 1999-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Osteoarchaeology (JOURNAL) |
| Journal identifiers | ISSN: 1047-482X • E-ISSN: 1099-1212 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/(sici)1099-1212(199901/02)9:1<1::aid-oa464>3.3.co;2-t |
| OpenAlex | W4250723120 |
| Language | EN |
| References cited | 15 |
The antiquity of rheumatoid arthritis (RA) is still in dispute, due to the difficulty of conclusively differentiating peripheral polyarthritis, especially from spondyloarthropathy, in archaeological populations. In view of the importance of genetic factors in developing spondyloarthropathy and of the far lower prevalence of the disease in modern Japanese, a rarity of peripheral polyarthritis would be anticipated in the ancient Japanese population, given that RA had not been present there. One hundred and sixty adult Japanese skeletons of the late and final Jomon period (3400–2400 years bp) were examined to find peripheral polyarthritis. There was one male skeleton with peripheral polyarthritis, showing marginal and surface erosions in the joints of the hands, feet, ankle and zygoapopheseal joints of the thoracic vertebrae. RA is suggested as the most probable cause of this pathology. This report raises the significance of further studies to consider whether more cases than anticipated exist in skeletal populations that would have been resistant to developing spondyloarthropathy. Copyright © 1999 John Wiley & Sons, Ltd.
Arthritis · Disease · Metatarsophalangeal joints · Paleopathology · Pathology · Peripheral · Polyarthritis · Population · Rheumatoid arthritis · Spondyloarthropathy · History of Medicine Studies · Immunology · Internal Medicine · Medical and Biological Sciences · Medicine · Musculoskeletal Disorders and Rehabilitation · Osteomyelitis and Bone Disorders Research · Spondyloarthritis Studies and Treatments · Surgery
| Highly cited | No |
|---|