Identification of monozygotic twin chimpanzees by microsatellite analysis
Bibliographic Data
| ID | 22898767 |
|---|---|
| Authors | Yunwu Zhang, Yun‐wu Zhang (0000-0002-7152-7630, Chinese Academy of Sciences), Simon K Lawrance (Otterbein University), Oliver A Ryder (0000-0003-2427-763X, Zoological Society of San Diego, corresponding author), Ya‐ping Zhang (0000-0002-5401-1114, Kunming Institute of Zoology), Yaping Zhang (0000-0002-3327-9111), Ramiro Isaza (Kansas State University) |
| Year | 2000 |
| Volume | 52 |
| Issue | 2 |
| Pages | 101-106 |
| Publication date | 2000-10-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Primatology (JOURNAL) |
| Journal identifiers | ISSN: 0275-2565 • E-ISSN: 1098-2345 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/1098-2345(200010)52:2<101::aid-ajp4>3.0.co;2-6 |
| PMID | 11051445 |
| OpenAlex | W1971253561 |
| Language | EN |
| Citations received | 2 |
| References cited | 16 |
Zygosity determination is important for epidemiological, biological, obstetric, and prognostic studies in both human and nonhuman primates. In this study, microsatellite loci were used to screen a pair of chimpanzee (Pan troglodytes) twins and their parents. The twins share identical alleles at all loci tested. The probability of dizygotic origin is estimated to be 2.9 x 10(-11). Even after excluding linkage of loci on the same chromosome, the probability is still low enough (3.7 x 10(-9)) to exclude dizygotic origin. MHC typing was also done on Patr-DRB and Patr-DQB loci and the twins share identical alleles at both loci, consistent with the microsatellite results. Together these results demonstrate a monozygotic origin for the chimp twins. Our results suggest that microsatellite analysis is a powerful method for zygosity determination, which can be screened reliably and efficiently.
Allele · Biology · Dizygotic twins · Evolutionary biology · Gene · Genetic linkage · Microsatellite · Monozygotic twin · Typing · Zygosity · Digital Imaging for Blood Diseases · Genetics · Medicine · Primate Behavior and Ecology · Zebrafish Biomedical Research Applications
| Unique citing works | 2 |
|---|---|
| Citations per year | 0,08 |
| Citation span | 2002 - 2006 (5) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 2 |