Protective effect of hydroalcoholic Crateva religiosa G. Forst. bark extract on oxidative stress, hormonal imbalance and gene expressions (CYP19A1 and PPARγ) in letrozole-induced polycystic ovarian syndrome rats
Bibliographic Data
| ID | 22917486 |
|---|---|
| Authors | Meenaloshini P (0009-0003-9560-3719), P Meenaloshini (Bharathidasan University, corresponding author), Ayyadurai Thirumurugan (0000-0003-4355-1569), Shanmugam Achiraman (0000-0002-6790-5205, Bharathidasan University), Thiruppathi Senthil Kumar (0000-0003-4967-0569, Bharathidasan University) |
| Year | 2025 |
| Volume | 353 |
| Issue | Pt A |
| Pages | 120354 |
| Publication date | 2025-09-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.120354 |
| PMID | 40759298 |
| OpenAlex | W4412989073 |
| Language | EN |
| References cited | 44 |
The therapeutic effect of C. religiosa bark extract helps to restore hormonal balance and promotes normal estrous cycles, in part by modulating the key genes such as CYP19A1 and PPARγ, highlighting its potential as a natural treatment for PCOS.
Bark (sound) · Biological activity · Biology · Hormone · In vitro · Oxidative stress · Pharmacognosy · Traditional medicine · Biochemistry · Cholesterol and Lipid Metabolism · Endocrinology · Estrogen and related hormone effects · Internal Medicine · Medicine · Pharmacology · Steroid Chemistry and Biochemistry
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| Citation velocity | historical |
|---|---|
| Highly cited | No |