Interaction of Zinc and Other Metal on the Activity of Erythrocyte Δ=amino-Levulinic Acid Dehydratase in Vitro
Bibliographic Data
| ID | 23205374 |
|---|---|
| Authors | Ali Arazeem Abdullahi (0000-0002-8304-3967), Katsumaro Tomokuni, Saka Luqman (0000-0002-7811-5268) |
| Year | 1979 |
| Volume | 4 |
| Issue | 1 |
| Pages | 11-17 |
| Publication date | 1979-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | The Journal of Toxicological Sciences (JOURNAL) |
| Journal identifiers | ISSN: 0388-1350 • E-ISSN: 1880-3989 |
| Publisher | Japanese Society of Toxicology (PUBLISHER • JP) |
| DOI | 10.2131/jts.4.11 |
| OpenAlex | W480402 |
| Language | EN |
| Citations received | 3 |
| References cited | 1 |
The interaction of zinc and other metal such as lead, mercury (II), cadmium, silver (II) on the activity of erythrocyte delta-aminolevulinic acid dehydratase (ALA-D) was investigated in vitro. At the concentrations ranging from 0.01 to 1.0 mmol/l, lead, mercury (II), cadmium and silver (II) strikingly inhibited the erythrocyte ALA-D activity. The in vitro addition of zinc having an activating effect for the erythrocyte ALA-D, was observed to eliminate the lead-induced inhibition of the erythrocyte ALA-D activity. And the degree of the elimination seemed to depend on the molar ratio (Zn/Pb) of both metal concentrations in the ALA-D assay. However, the inhibition of erythrocyte ALA-D activity caused by mercury (II), cadmium and silver (II) was not removed by the in vitro addition of zinc.
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| Unique citing works | 3 |
|---|---|
| Citations per year | 0,25 |
| Citation span | 2014 - 2019 (6) |
| Citation velocity | historical |
| Highly cited | No |