More than 50 long-term effects of Covid-19
A systematic review and meta-analysis
Bibliographic Data
| ID | 23320199 |
|---|---|
| Authors | Sandra Lopez-Leon (0000-0001-7504-3441), Talia Wegman-Ostrosky (0000-0002-3207-6697), Carol Perelman (0000-0002-0111-1154), Rosalinda Sepulveda (0000-0003-1146-9552), Paulina A Rebolledo (0000-0002-9808-063X), Angelica Cuapio (0000-0002-9451-1914), Sonia Villapol (0000-0002-6174-4113) |
| Year | 2021 |
| Volume | 11 |
| Issue | 1 |
| Publication date | 2021-08-09 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Scientific Reports (JOURNAL) |
| Journal identifiers | ISSN: 2045-2322 • E-ISSN: 2045-2322 |
| Publisher | Springer Science and Business Media LLC (PUBLISHER) |
| DOI | 10.1038/s41598-021-95565-8 |
| Language | EN |
| Citations received | 103 |
| References cited | 51 |
COVID-19 can involve persistence, sequelae, and other medical complications that last weeks to months after initial recovery. This systematic review and meta-analysis aims to identify studies assessing the long-term effects of COVID-19. LitCOVID and Embase were searched to identify articles with original data published before the 1st of January 2021, with a minimum of 100 patients. For effects reported in two or more studies, meta-analyses using a random-effects model were performed using the MetaXL software to estimate the pooled prevalence with 95% CI. PRISMA guidelines were followed. A total of 18,251 publications were identified, of which 15 met the inclusion criteria. The prevalence of 55 long-term effects was estimated, 21 meta-analyses were performed, and 47,910 patients were included (age 17–87 years). The included studies defined long-COVID as ranging from 14 to 110 days post-viral infection. It was estimated that 80% of the infected patients with SARS-CoV-2 developed one or more long-term symptoms. The five most common symptoms were fatigue (58%), headache (44%), attention disorder (27%), hair loss (25%), and dyspnea (24%). Multi-disciplinary teams are crucial to developing preventive measures, rehabilitation techniques, and clinical management strategies with whole-patient perspectives designed to address long COVID-19 care.
Identifying long-term effects of Sars-CoV-2 and their association with social determinants of health in a cohort of over one million Covid-19 survivors
Impact of pre-pandemic sick leave diagnoses on the length of Covid-19-related sick leave
Prevalence of Post-Covid conditions among Mexican Covid-19 survivors
Illness presentation and quality of life in myalgic encephalomyelitis/chronic fatigue syndrome and post Covid-19 condition
Symptoms and risk factors for long Covid in non-hospitalized adults
Impact of Covid-19 Infection on Health-Related Quality of Life in the Japanese Population
Impact of Unexpected In-House Major Covid-19 Outbreaks on Depressive Symptoms among Healthcare Workers
The Treaty of Guadalupe Hidalgo and the California Indians
Modelling the potential acute and post-acute burden of Covid-19 under the Australian border re-opening plan
Covid-19 Worsens Chronic Lumbosacral Radicular Pain—Case Series Report
Impact of Covid-19 on Health-Related Quality of Life
Molecular Hydrogen Positively Affects Physical and Respiratory Function in Acute Post-Covid-19 Patients
One-year trajectories of physical and mental health-related quality of life, fatigue and dyspnoea in Covid-19 survivors
Trajectories of health-related quality of life and their predictors in adult Covid-19 survivors
Psychiatric hospitalizations in the Unified Health System
Vertebral Algic Syndrome Treatment in Long Covid—Cases Reports
Mental Health Issues as a Consequence of the Pandemic
Exploring the association between the post-pandemic period and psychological problems among university students in Wuhan
Fear of Death during Covid-19 Does Not Explain Post-Infection Depression Symptoms beyond Reported Symptoms during the Infection in Covid-19 Survivors
Prevalence and Associated Factors of Post-Covid-19 Syndrome in a Brazilian Cohort after 3 and 6 Months of Hospital Discharge
Long-term effects on physical and mental health and work ability after Covid-19 versus other upper respiratory infections
Long-Term Health Effects of Covid-19 in Tunisia, 2020–2021
Perceived Consequences of Post-Covid-19 and Factors Associated with Low Life Satisfaction
Characterising disability in patients with long Covid–does gender matter? an analytic cross-sectional study
One-year follow-up of depression, anxiety, and quality of life of Peruvian patients who survived Covid-19
Covid-19 Public Opinion
Physical as Well as Psychological Distress and Coping with Situational Dilemmas Experienced by People Infected with Covid-19
Patients’ Health Experiences of Post Covid-19 Condition—A Qualitative Study
Pre-pandemic lifestyle patterns and mental health outcomes among people reporting post-acute sequelae of Covid-19
Proprietary Model of Qualification for In-Hospital Rehabilitation after Covid-19
Fatigue and physical activity levels in poles living in Poland and the United Kingdom in the further year of the Covid-19 pandemic
One-Year Adverse Outcomes Among US Adults With Post–Covid-19 Condition vs Those Without Covid-19 in a Large Commercial Insurance Database
Health-Related Quality of Life Among Patients Recovered From Covid-19
Long-Term Effects of Covid-19 on Workers in Health and Social Services in Germany
Post Covid-19 condition and health-related quality of life
Long-Term Symptoms after Mild Coronavirus Disease in Healthy Healthcare Professionals
Associations between Covid-19 Pandemic, Lockdown Measures and Human Mobility
Association between Adverse Childhood Events (ACEs) and long-term Covid-19 symptoms
It Really Is an Elusive Illness”—Post-Covid-19 Illness Perceptions and Recovery Strategies
Awareness and care seeking for long Covid symptoms among Coronavirus disease survivors in Bahir Dar City, Northwest Ethiopia
A bit of a cough, tired, not very resilient – is that already Long-Covid?” perceptions and experiences of GPs with Long-Covid in year three of the pandemic. a qualitative interview study in Austria
It was almost like it’s set up for people to fail” A qualitative analysis of experiences and unmet supportive needs of people with Long Covid
Mental Fatigue, Activities of Daily Living, Sick Leave and Functional Status among Patients with Long Covid
Prevalence and exploratory factor analysis of long Covid-19 symptoms among experienced infected population in Bangkok, Thailand
Anxiety and posttraumatic stress in post-acute sequelae of Covid-19
Safety and Efficacy of Pulmonary Rehabilitation for Long Covid Patients Experiencing Long-Lasting Symptoms
Social Stigma, Mental Health, Stress, and Health-Related Quality of Life in People with Long Covid
Estimating the direct Covid-19 disability-adjusted life years impact on the Malta population for the first full year
Lowered Quality of Life in Long Covid Is Predicted by Affective Symptoms, Chronic Fatigue Syndrome, Inflammation and Neuroimmunotoxic Pathways
Effectiveness of two interventions to optimize expectations in psychosomatic rehabilitation of post-Covid patients
The Feasibility and Impact of Practising Online Forest Bathing to Improve Anxiety, Rumination, Social Connection and Long-Covid Symptoms
Deciphering Multifactorial Correlations of Covid-19 Incidence and Mortality in the Brazilian Amazon Basin
Liaison Psychiatry During the Peak of the Coronavirus Pandemic
Toward characterizing brain fog in long Covid
Deep Dive into the Long Haul
Brain Fog and Fatigue following Covid-19 Infection
Risk factors associated with post-acute sequelae of Sars-CoV-2
Retrospective Analysis of the Outcome of Hospitalized Covid-19 Patients with Coexisting Metabolic Syndrome and HIV Using Multinomial Logistic Regression
Psychological interventions for individuals with long Covid
Intergenerational fairness
Covid-19 and mental health
Recent Chronology of Covid-19 Pandemic
Is Endemicity a Solution for the Covid-19 Pandemic? The Four E's Strategy for the Public Health Leadership
Tinnitus and Covid-19
Long Covid and its associations with burnout, anxiety, and depression among U. S. healthcare workers in the United States
Post-acute Covid-19 symptom risk in hospitalized and non-hospitalized Covid-19 survivors
Covid-19 vaccination status in Germany
Post-infection symptoms up to 24 months after Covid-19
Post-Covid-19 fatigue and health-related quality of life in Saudi Arabia
Mental symptoms in post-Covid syndrome and post-Covid-19 vaccination syndrome
German nationwide inpatient data on the post-Covid-19 syndrome
Post-Covid-19 syndrome and quality of life impairment in severe Covid-19 Mexican patients
Characterizing health-related quality of life and identifying disease predictors among patients suspected of having long Covid
Age at Sars-CoV-2 infection and psychological and physical recovery among Chinese health care workers with severe Covid-19 at 28 months after discharge
Eighteen months into the Covid-19 pandemic
Long-term effects of Covid-19 in diabetic and non-diabetic patients
Neuropsychiatric Constructs as Bridges Between Psychopathology and Neuropathology
Substance Use and the Self-Management of Persistent Symptoms of Covid-19
Covid-19 Vaccines #ForYou
El impacto de la pandemia de Covid-19 sobre la salud. Informe Sespas 2022
Long covid and medical gaslighting
Work, telework, and mental health during Covid-19
Comparative study of quality of life 9 months post-Covid-19 infection with Sars-CoV-2 of varying degrees of severity
Suffering without Remedy
Medical gaslighting
Covid-19 worry and smoking processes among Hispanic persons in the United States
Selected Factors of Psychological Reactions Among Polish Respondents to the Outbreak of Covid-19 Pandemic
The association of Sars-CoV-2 infection and tuberculosis disease with unfavorable treatment outcomes
Post-Covid-19 syndrome risk factors and further use of health services in East England
Symptoms and signs of long Covid
Prevalence and risk factors for long Covid after mild disease
Prevalence and duration of common symptoms in people with long Covid
Post-Covid symptom profiles and duration in a global convalescent Covid-19 observational cohort
Lived Experiences of New‐Onset Long Covid Pain and Its Impact on Health‐Related Quality of Life. A Scoping Review of Current Evidence
Prepandemic Resilience to Trauma and Covid-19 Infection in Older Women
The social evolution of Covid-19
Trabajo, teletrabajo y salud mental en el contexto Covid-19
Prevalence of persistent symptoms after having Covid-19 in a cohort in Suriname
Prevalence and factors associated with long Covid in adults from Southern Brazil
Socioeconomic disparities in long Covid diagnosis among ethnic minorities in Denmark
Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015
Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections
Bidirectional associations between Covid-19 and psychiatric disorder
Persistent Symptoms in Patients After Acute Covid-19
Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (Pace)
Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with Covid-19 in a Multistate Health Care Systems Network — United States, March–June 2020
Management of post-acute covid-19 in primary care
Insomnia in the Italian Population During Covid-19 Outbreak
Persistence of Covid-19 Symptoms after Recovery in Mexican Population
Meta-analysis of prevalence
| Unique citing works | 103 |
|---|---|
| Citations per year | 2,06 |
| Citation span | 1976 - 2026 (51) |
| Citation velocity | current |
| Highly cited | Yes |
| Citation types | Neutral: 103 |