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Salivary alpha-amylase as a non-invasive biomarker for the sympathetic nervous system

Current state of research

Bibliographic Data

ID23326430
AuthorsUrs M Nater (0000-0002-2430-5090, University of Zurich, corresponding author), Nicolas Rohleder (0000-0003-2602-517X, Brandeis University)
Year2009
Volume34
Issue4
Pages486-496
Publication date2009-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePsychoneuroendocrinology (JOURNAL)
Journal identifiersISSN: 0306-4530 • E-ISSN: 1873-3360
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.psyneuen.2009.01.014
PMID19249160
OpenAlexW1989439371
LanguageEN
Citations received76
References cited96

Autonomic nervous system · Biology · Biomarker · Heart rate · Nervous system · Physics · Reliability (semiconductor) · Sympathetic nervous system · Heart Rate Variability and Autonomic Control · Internal Medicine · Medicine · Neuroscience · Psychology · Stress Responses and Cortisol · Tryptophan and brain disorders

  • Measuring short-term changes in stress-associated salivary analytes in free-ranging Japanese macaques (Macaca fuscata)

    Open Access•Nelson Broche, Keiko Mouri et al.•Primates•2023

  • The Relationship of Level of Traumatic Exposure, Perceived Stress, and Resilience with Salivary Cortisol and Salivary Alpha-Amylase Diurnal Rhythm in Palestinian Children 10-12 Years Exposed to Chronic War Violence

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  • The Relationship of Level of Traumatic Exposure, Perceived Stress, and Resilience with Salivary Cortisol and Salivary Alpha-Amylase Diurnal Rhythm in Palestinian Children 10-12 Years Exposed to Chronic War Violence

    Mohammad Asia•2009

  • Evaluation of salivary alpha-amylase level in patients undergoing surgical extraction of impacted lower wisdom teeth

    Open Access•Falah Hasan Jumaah, Sahar Shakir Al-Adili•International Journal of Health…•2022

  • Effects of Cardiorespiratory Fitness and Obesity on Salivary Secretory IgA and Alpha-Amylase in South African Children

    Open Access•Dorota E Starzak, Kristen F Konkol et al.•Children•2016

  • Acute Physiological and Psychological Stress Response in Youth at Clinical High-Risk for Psychosis

    Open Access•Emily E Carol, Robert L Spencer et al.•Frontiers in Psychiatry•2021

  • The Influence of Forest Resting Environments on Stress Using Virtual Reality

    Open Access•Xiaobo Wang, Yaxing Shi et al.•International Journal of…•2019

  • Variations in Salivary Stress Biomarkers and Their Relationship with Anxiety, Self-Efficacy and Sleeping Quality in Emergency Health Care Professionals

    Open Access•Daniel Pérez-Valdecantos, Alberto Caballero-García et al.•International Journal of…•2021

  • Are narcissists hardy or vulnerable? The role of narcissism in the production of stress-related biomarkers in response to emotional distress

    Joey T Cheng, Jessica L Tracy et al.•Emotion•2013

  • The effects of interpersonal emotional expression, partner responsiveness, and emotional approach coping on stress responses

    Heidi S Kane, Joshua F Wiley et al.•Emotion•2018

  • Effects of stress on decisions under uncertainty

    Katrin Starcke, Matthias Brand•Psychological Bulletin•2016

  • Stress and Human Biology

    Gillian H Ice, Gary D James•Human Biology•2012

  • Decision making under stress

    Open Access•Katrin Starcke, Matthias Brand•Neuroscience & Biobehavioral…•2012

  • Affectionate Touch to Promote Relational, Psychological, and Physical Well-Being in Adulthood

    Open Access•Brett K Jakubiak, Brooke C Feeney•Personality and Social Psychology…•2017

  • Urban Nature Experiences Reduce Stress in the Context of Daily Life Based on Salivary Biomarkers

    Open Access•MaryCarol R Hunter, Brenda W Gillespie et al.•Frontiers in Psychology•2019

  • The effect of virtual reality forest and urban environments on physiological and psychological responses

    Open Access•Chia-Pin Yu, Hsiao‐Yun Lee et al.•Urban Forestry & Urban Greening•2018

  • Changes in Markers of Oxidative Stress and α-Amylase in Saliva of Children Associated with a Tennis Competition

    Open Access•José María Giménez‐Egido, Raquel Hernández‐García et al.•International Journal of…•2020

  • Stress management training for managers in small and medium-sized enterprises (KMU-GO)

    Open Access•Sophie Hofmann, Svenja Schlachter et al.•BMC Public Health•2026

  • Salivary Diagnostic for Monitoring Strenuous Exercise—A Pilot Study in a Cohort of Male Ultramarathon Runners

    Open Access•Josephin Borchers, Cordula Leonie Merle et al.•International Journal of…•2022

  • Evaluation of the Effect of a Live Interview in Journalism Students on Salivary Stress Biomarkers and Conventional Stress Scales

    Open Access•Delfina Roca Marín, Delfina Roca et al.•International Journal of…•2022

  • Does workplace telepressure get under the skin? Protocol for an ambulatory assessment study on wellbeing and health-related physiological, experiential, and behavioral concomitants of workplace telepressure

    Open Access•Raphaël Semaan, Urs M Nater et al.•BMC Psychology•2023

  • Salivary Biomarkers in Pediatric Acute Appendicitis

    Open Access•Zenon Pogorelić, Miro Jukić et al.•Children•2025

  • Salivary α-Amylase Reactivity to Infant Crying in Maltreating Mothers

    Open Access•Sophie Reijman, Lenneke R A Alink et al.•Child Psychiatry & Human…•2014

  • Instructed Partnership Appreciation in Depression

    Open Access•Marco Warth, M Stoffel et al.•Frontiers in Psychiatry•2020

  • Maternal Correlates of Children’s Stress Functioning Following a Major Natural Disaster

    Jacob M Vigil, A C Carle et al.•Journal of Child & Adolescent…•2009

  • Study protocol

    Open Access•Simone Munsch•BMC Psychology•2014

  • Stress/Immune Biomarkers in Saliva among Children with ADHD Status

    Open Access•Anna Krahel, Elżbieta Paszyńska et al.•International Journal of…•2021

  • Active Shooter Training Drill Increases Blood and Salivary Markers of Stress

    Open Access•Matthew J Mcallister, M Hunter Martaindale et al.•International Journal of…•2020

  • Salivary Alpha-Amylase Reactivity in Breast Cancer Survivors

    Open Access•Cynthia Wan, Marie-Ève Couture-Lalande et al.•International Journal of…•2016

  • Does childhood trauma impact daily psychobiological stress in somatic symptom disorder? An ambulatory assessment study

    Open Access•Susanne Fischer, Nida Ali et al.•Frontiers in Psychiatry•2022

  • Stress-Related Responses to Alternations between Repetitive Physical Work and Cognitive Tasks of Different Difficulties

    Open Access•Susanna Mixter, Svend Erik Mathiassen et al.•International Journal of…•2020

  • Effects of Green Color Exposure on Stress, Anxiety, and Pain during Peripheral Intravenous Cannulation in Dental Patients Requiring Sedation

    Open Access•Yukihiko Takemura, Kanta Kido et al.•International Journal of…•2021

  • Reliability and validity of the Adolescent Stress Questionnaire in a sample of European adolescents - the Helena study

    Open Access•Tineke De Vriendt, Els Clays et al.•BMC Public Health•2011

  • Salivary Enzymatic Activity and Carious Experience in Children

    Open Access•Raluca-Paula Vacaru, Andreea Cristiana Didilescu et al.•Children•2022

  • Subjective and objective stress during body exposure

    Open Access•Valeska Stonawski, Louisa Kuper et al.•Frontiers in Psychiatry•2025

  • Is Salivary pH a Marker of Depression among Older Spousal Caregivers for Cancer Patients

    RABIA KHALAILA, Miri Cohen et al.•Behavioral Medicine•2013

  • Nature-based interventions reduce physiological stress in children with chronic illnesses

    Open Access•Francisco Díaz-Martínez, Miguel Felipe Sánchez Sauco et al.•Frontiers in Public Health•2025

  • Effects of Linpan nature therapy on health benefits in older women with and without hypertension

    Open Access•Ye Xiang, Xiang Ye et al.•Frontiers in Public Health•2023

  • Media Multitasking in Younger and Older Adults

    Open Access•Wienke Wannagat, Tamara Martin et al.•Media Psychology•2025

  • Salivary Cortisol and α-Amylase Production at Awakening is Associated with Positivity (POS) Levels in Healthy Young Subjects

    Open Access•Vittorio Pasquali, Cristina Mihaela Ghiciuc et al.•Journal of Happiness Studies•2021

  • Evidence of the Associations between Individual and Partner Autonomy Support and Physiological Stress in the Context of Conversations about Weight among Couples Who are Overweight or Obese during a 6-Month Intervention

    A Denes, J P Crowley et al.•Health Communication•2022

  • How is mental health associated with adolescent alpha-amylase and cortisol reactivity and coordination

    Open Access•Mervi Vänskä, Samuli Kangaslampi et al.•International Journal of…•2024

  • Examining biomarkers of stress over the process of teaching among teachers of English as a foreign language

    Open Access•Ali Mansouri Nejad, Omer Hassan Ali Mahfoodh•Psychology in the Schools•2024

  • An Experimental Test of the Effects of Fear in a Coordination Game

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  • Religious-Commitment Signaling and Impression Management amongst Pentecostals

    C D Lynn, Jason J Paris et al.•Journal of Cognition and Culture•2015

  • Influence of an art museum visit on individuals’ psychological and physiological indicators of stress

    Kristina Ter-Kazarian, Jessica J Luke•Museums & Social Issues•2019

  • Spousal Presence Modulates Salivary α-Amylase Responses to Infant Cry in Mothers With High Attachment Insecurity

    Daiki Hiraoka, Mami Miyasaka et al.•Parenting•2019

  • Beyond catecholamines

    Open Access•Jason A Decaro•American Journal of Human Biology•2015

  • Classroom Emotional Support predicts differences in preschool children's cortisol and alpha-amylase levels

    Open Access•Bridget E Hatfield, Linda L Hestenes et al.•Early Childhood Research Quarterly•2012

  • Mind the gap between feeling bad and feeling dead

    Benjamin Buttlar, Eva Walther et al.•Death Studies•2020

  • Parents' Communication Skills and Adolescents' Salivary α-Amylase and Cortisol Response Patterns

    T D Afifi, Douglas A Granger et al.•Communication Monographs•2011

  • The longitudinal influence of supportive messages on stress reactivity and general well-being for LGBTQ+ recipients of hate speech

    J P Crowley, A Denes et al.•Communication Monographs•2023

  • What do two men kissing and a bucket of maggots have in common? Heterosexual men’s indistinguishable salivary α-amylase responses to photos of two men kissing and disgusting images

    Breanna Maureen O’Handley, Karen L Blair et al.•Psychology and Sexuality•2017

  • Self-compassionate young adults show lower salivary alpha-amylase responses to repeated psychosocial stress

    Juliana G Breines, Christine McInnis et al.•Self and Identity•2015

  • Associations between the awakening responses of salivary α-amylase and cortisol with self-report indicators of health and wellbeing among educators

    Open Access•Deirdre A Katz, Mark T Greenberg et al.•Teaching and Teacher Education•2015

  • Does acute psychosocial stress alter risk-taking behavior under competitive conditions? – An experimental pilot study

    Open Access•Bence Szaszkó, Charlotte Muller et al.•Acta Psychologica•2025

  • Factors affecting salivary α‐amylase levels measured with a handheld biosensor and a standard laboratory assay

    Open Access•Kanlayanee Tangprasert, Nattinee Jantaratnotai et al.•American Journal of Human Biology•2019

  • Saliva sampling method affects performance of a salivary α‐amylase biosensor

    Open Access•Theodore F Robles, Rassilee Sharma et al.•American Journal of Human Biology•2013

  • Salivary alpha‐amylase activity and stress in Japan air self‐defense force cargo pilots involved in Iraq reconstruction

    Open Access•Naotaka Iizuka, Shuji Awano et al.•American Journal of Human Biology•2012

  • Salivary alpha‐amylase and cortisol among pentecostals on a worship and nonworship day

    Open Access•C D Lynn, Jason J Paris et al.•American Journal of Human Biology•2010

  • The Use of Smartphones as a Digital Security Blanket

    John F Hunter, Emily D Hooker et al.•Psychosomatic Medicine•2018

  • Perceived Social Support and Children’s Physiological Responses to Stress

    Lihua Chen, Samuele Zilioli et al.•Psychosomatic Medicine•2021

  • Β-Adrenergic Contributions to Emotion and Physiology During an Acute Psychosocial Stressor

    Jennifer K MacCormack, Emma Armstrong‐carter et al.•Psychosomatic Medicine•2021

  • The Acute Autonomic Stress Response and Amniotic Fluid Glucocorticoids in Second-Trimester Pregnant Women

    Pearl La Marca-Ghaemmaghami, Sara M Dainese et al.•Psychosomatic Medicine•2015

  • Stress-Induced Suppression of Food Intake in Overweight and Obese Adolescents

    Matthew Nagy, Matthew R Nagy et al.•Psychosomatic Medicine•2019

  • Psychobiological Mechanisms in Somatic Symptom Disorder and Depressive Disorders

    Ricarda Mewes, Anja C Feneberg et al.•Psychosomatic Medicine•2022

  • Stress-Induced Cortisol Level Elevations Are Associated With Reduced Negative Affect After Stress

    Serkan Het, Daniela Schoofs et al.•Psychosomatic Medicine•2012

  • Characteristics of Autonomic Activity and Reactivity During Rest and Emotional Processing and Their Clinical Correlations in Somatic Symptom Disorder

    Deokjong Lee, Se Joo Kim et al.•Psychosomatic Medicine•2018

  • Effects of Head Inclination and Focal Length on Emotional State and Degree of Stress 1

    Open Access•Tomohiro Suzuki, Hidetoshi Maie et al.•Japanese Psychological Research•2023

  • Psychological endurance

    Adam T Biggs, Todd R Seech et al.•The Journal of General Psychology•2023

  • Glossolalia is associated with differences in biomarkers of stress and arousal among Apostolic Pentecostals

    C D Lynn, Jason J Paris et al.•Religion Brain & Behavior•2011

  • Victimization and Biological Stress Responses in Urban Adolescents

    Open Access•Wendy Kliewer•Journal of Youth and Adolescence•2016

  • Rethinking the starch digestion hypothesis for AMY1 copy number variation in humans

    Open Access•Catalina I Fernández, Andrea S Wiley•American Journal of Physical…•2017

  • Perspective-taking influences autonomic attunement between partners during discussion of conflict

    Open Access•Benjamin W Nelson, Sean M Laurent et al.•Journal of Social and Personal…•2016

  • Salivary Markers of Stress in Grandparents Rearing Grandchildren in Rural Appalachia

    Kyle P Rawn, Peggy S Keller et al.•Journal of Intergenerational…•2023

  • Couple Identity Gaps, the Management of Conflict, and Biological and Self-Reported Stress in Romantic Relationships

    Open Access•Anne F Merrill, Tamara D Afifi•Human Communication Research•2017

  • Salivary Cortisol in Psychobiological Research

    Open Access•Clemens Kirschbaum, Dirk H Hellhammer•Neuropsychobiology•2008

  • Salivary cortisol in psychoneuroendocrine research

    Open Access•Clemens Kirschbaum, Dirk H Hellhammer•Psychoneuroendocrinology•1994

  • The ‘Trier Social Stress Test’ – A Tool for Investigating Psychobiological Stress Responses in a Laboratory Setting

    Open Access•Clemens Kirschbaum, Karl-Martin Pirke et al.•Neuropsychobiology•2008

  • Psychological Stress as a Determinant of Protein Levels and Salivary-Induced Aggregation of Streptococcus gordonii in Human Whole Saliva

    Jos A Bosch, H S Brand et al.•Psychosomatic Medicine•1996

  • Psychophysiology of the posttraumatic stress disorder

    Arieh Y Shalev, Y Rogel-Fuchs et al.•Psychosomatic Medicine•1993

  • Innate Secretory Immunity in Response to Laboratory Stressors That Evoke Distinct Patterns of Cardiac Autonomic Activity

    Jos A Bosch, Eco J C De Geus et al.•Psychosomatic Medicine•2003

  • Patients With Erythrophobia (Fear of Blushing) Show Abnormal Autonomic Regulation in Mental Stress Conditions

    Kurt Laederach, Kurt Laederach-Hofmann et al.•Psychosomatic Medicine•2002

  • Integrating the measurement of salivary α-amylase into studies of child health, development, and social relationships

    Open Access•Douglas A Granger, Katie T Kivlighan et al.•Journal of Social and Personal…•2006

Unique citing works76
Citations per year4,47
Citation span2009 - 2026 (18)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 65

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