The “All of Us” Research Program
Bibliographic Data
| ID | 23330490 |
|---|---|
| Authors | The All of Us Research Program Investigators (National Human Genome Research Institute, corresponding author) |
| Year | 2019 |
| Volume | 381 |
| Issue | 7 |
| Pages | 668-676 |
| Publication date | 2019-08-15 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | New England Journal of Medicine (JOURNAL) |
| Journal identifiers | ISSN: 0028-4793 • E-ISSN: 1533-4406 |
| Publisher | Massachusetts Medical Society (PUBLISHER • US) |
| DOI | 10.1056/nejmsr1809937 |
| PMID | 31412182 |
| OpenAlex | W4205170775 |
| Language | EN |
| Citations received | 65 |
| References cited | 34 |
Knowledge gained from observational cohort studies has dramatically advanced the prevention and treatment of diseases. Many of these cohorts, however, are small, lack diversity, or do not provide comprehensive phenotype data. The All of Us Research Program plans to enroll a diverse group of at least 1 million persons in the United States in order to accelerate biomedical research and improve health. The program aims to make the research results accessible to participants, and it is developing new approaches to generate, access, and make data broadly available to approved researchers. All of Us opened for enrollment in May 2018 and currently enrolls participants 18 years of age or older from a network of more than 340 recruitment sites. Elements of the program protocol include health questionnaires, electronic health records (EHRs), physical measurements, the use of digital health technology, and the collection and analysis of biospecimens. As of July 2019, more than 175,000 participants had contributed biospecimens. More than 80% of these participants are from groups that have been historically underrepresented in biomedical research. EHR data on more than 112,000 participants from 34 sites have been collected. The All of Us data repository should permit researchers to take into account individual differences in lifestyle, socioeconomic factors, environment, and biologic characteristics in order to advance precision diagnosis, prevention, and treatment.
Alternative medicine · Data collection · Data science · Diversity (politics) · Environmental health · Family medicine · Health care · Health equity · Health records · Medical education · Observational study · Political science · Population · Protocol (science) · Public health · Research program · Socioeconomic status · Cardiovascular Health and Risk Factors · Computer Science · Health, Environment, Cognitive Aging · Machine Learning in Healthcare · Medicine · Nursing · Psychology · Gerontology
Differences in Healthcare and Everyday Discrimination among Racial and Ethnic Minority Cancer Survivors in the all of the US Research Program
Increased risk of smoking and pain in individuals with intermittent explosive disorder in the All of Us dataset
From genomics to clinical practice
Combined Effects of Arsenic, Cadmium, and Mercury with Cardiovascular Disease Risk
Consent for Use of Genetic Data among US Hispanics/Latinos
Care and Precision Medicine Research in the Time of Covid-19
The Use of Racial Categories in Precision Medicine Research
Personality traits and health care use
A multilevel analysis of LGBT-relevant laws and sexual and gender minority mental health
Cancer health disparities in racial/ethnic minorities in the United States
Machine learning approaches to racial/ethnic differences in social determinants of mild cognitive impairment and its progression to dementia in the All of Us Research Program
Sexual orientation, gender identity and virologic failure among people with HIV
Early-stage economic analysis of research-based comprehensive genomic sequencing for advanced cancer care
A Framework for Promoting Diversity, Equity, and Inclusion in Genetics and Genomics Research
A Comparative Analysis of Oral Health and Self-Rated Health
Association between GLP-1 receptor agonist use and substance use disorders among individuals with type 2 diabetes or obesity
Examining Coping Behaviors Associated with Depression among People with Type 2 Diabetes from May-July 2020
Relative predictive value of sociodemographic factors for chronic diseases among All of Us participants
Toward the Next Generation of Precision Medicine
Linking coastal environmental and health observations for human wellbeing
The U.S. Needs a National Human Health Observing System
Framework for a Community Health Observing System for the Gulf of Mexico Region
The National Children's Study Archive Model
Mini-Review of Laboratory Operations in Biobanking
Applying Engagement Marketing and Human-Centered Design to Cocreate a Digital Decision Support Tool for Research Participation with LGBTQIA+ Community Members
Precision medicine and the problem of structural injustice
Primary Care Providers’ Experiences With an Active Elective Genetic Testing Program
Discrimination, Stress, and Substance Use Among Ethnoracial Minority Gay, Bisexual, and Other Men Who Have Sex with Men
Collecting Biospecimens and Obtaining Biobank Consent From Patients in an Academic Health Care Setting
Innovation in Large-Scale Research Programs
The truth-default is ubiquitous, but some people experience it more than others
Donating with eyes shut”
Promoting Inclusive Recruitment
Pearl lecture
Exploring the intersection of gender with walking, the built environment, and health outcomes via the All of Us dataset
Health Literacy by Hispanic Ethnicity and its Association with Healthcare Experiences, Self-rated Health, and Quality of Life
Returning value to communities from the All of Us Research Program through the lens of social determinants of health and ethical, legal, and social implications
Intersectionality matters for Hispanic health
Discrimination and Mental Health Among Black and Latino People Living with HIV
Delays in Care by Race, Ethnicity, and Gender Before and During the Covid-19 Pandemic Using Cross-Sectional Data From the National Institutes of Health's All of Us Research Program
Marginalized measures
Re-imagining health research to include the voices of justice-impacted individuals
Cultivating Authentic Partnership
Structural patterns of intersectional stigma among sexual and gender minorities
Women's experience with gender‐based discrimination, social support, and health outcomes
Healthcare Acceptability and Delayed Care Among Older People Living with HIV in the All of Us Program
Tracing the Origins of Human Disease
How rural is All of Us ? Comparing characteristics of rural participants in the National Institute of Health's All of Us Research Program to other national data sources
A Systematic Review of the Influence of Social Determinants of Health on Mental Health Service Utilization and Outcomes Among Asian American Cancer Survivors
Human height
SHIFTing artificial intelligence to be responsible in healthcare
A social and ethical framework for providing health information obtained from combining genetics and fitness tracking data
Now, More Than Ever, We Need Institutional Commitments to Transgender Health Research
The Way Forward to Embrace Artificial Intelligence in Public Health
Community Engagement Alliance (Ceal)
Identification of Transgender and Gender-Diverse Individuals in the All of Us Research Program, 2017–2022
National Institutes of Health Advancing Multimorbidity Research
Leveraging genetic ancestry to study health disparities
Comparison of Demographic and Clinical Features of Bipolar Disorder in Persons of African and European Ancestry
Sexual identity differences in ideal cardiovascular health among cisgender adults in the All of Us Research Program
How Friction Led to a More Intentional Stakeholder Feedback Model for a Federal Research Program
New Data Sources for Demographic Research
We need more-diverse biobanks to improve behavioural genetics
Toward labor-sensitive research
Measurement opportunities for studying sexual and gender diverse partnerships in population-based surveys
| Unique citing works | 65 |
|---|---|
| Citations per year | 9,29 |
| Citation span | 2019 - 2026 (8) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 57 |