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Phytochemical Characterization and Antipyretic and Antinociceptive Activities of Echinops orientalis Trautv. Methanolic Flower Extract

Evidence from In vivo Studies, Network Pharmacology and Molecular Docking

Bibliographic Data

ID24214596
AuthorsZhawen Noori Hussein (0009-0005-2091-0807), Pshtiwan Ghareb Ali, Twana Mohsin Salih (0000-0002-7684-8601), Karmand Salih Hamaamin, Hastyar Hama Rashid Najmuldeen, Bushra Hassan Marouf (0000-0002-7658-9013), Saman Abdulrahman Ahmad, Sakar Yassin Hama Rahim, Sima Rahman Qadir (0009-0002-3819-3699), Mohammed Koksh Sidiq, Sara Fayaq Fariq
Year2026
Pages122415
Publication date2026-09-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2026.122415
PMID42790557
OpenAlexW7214313258
LanguageEN
References cited68

acetic acid-induced writhing · AKT1 · antinociceptive activity · antipyretic activity · Apigenin · Chlorogenic acid · cyclooxygenase-2 · EGFR · fever · flavonoids · formalin test · inflammatory signaling · interleukin-6 · methanolic flower extract · molecular docking · network pharmacology · phytochemical profiling · Prostaglandin E2 receptor · Quercetin · Src kinase · STAT3 · Thiophene · thromboxane synthase · Traditional medicine · Medicinal Plant Research · Phytochemistry and Biological Activities · Phytochemistry Medicinal Plant Applications

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