Integrating GC-MS analysis, Admet, and in vivo experimental validation to deciphering the toxicological profile of the aqueous extract of the mixture of Dacryodes edulis (G. Don) H.J. Lam (Burseraceae) and Allium ampeloprasum var. porrum L. (Amaryllidaceae)
Bibliographic Data
| ID | 24227654 |
|---|---|
| Authors | Segolene Flore Kengne (0009-0009-3587-2697), Danielle Claude Bilanda (0000-0003-2963-9994), Leonard Tedong, Rivaldo Bernes Kahou Tadah (0009-0008-1287-8976), Pascal Emmanuel Owona (0000-0002-0233-5299), Joseph Rodrigue Ngapout Fifen, Dzeufiet Djomeni Paul Désiré (0000-0001-5315-6285), Pierre Kamtchouing (0000-0001-7544-427X) |
| Year | 2026 |
| Volume | 360 |
| Pages | 121181 |
| Publication date | 2026-04-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2026.121181 |
| PMID | 41548620 |
| OpenAlex | W7124430047 |
| Language | EN |
| References cited | 62 |
Acute toxicity · aqueous plant extract · Cardiotoxicity · Chronic toxicity · cytochrome P450 inhibition · Cytotoxicity · Dacryodes edulis · hepatotoxicity · herbal medicine safety · Nephrotoxicity · pharmacokinetic prediction · phytochemical screening · toxicological profile · traditional medicine validation · Medicinal Plant Research · Phytochemical Studies and Bioactivities · Phytochemistry Medicinal Plant Applications
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| Highly cited | No |
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