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Integrating GC-MS analysis, Admet, and in vivo experimental validation to deciphering the toxicological profile of the aqueous extract of the mixture of Dacryodes edulis (G. Don) H.J. Lam (Burseraceae) and Allium ampeloprasum var. porrum L. (Amaryllidaceae)

Bibliographic Data

ID24227654
AuthorsSegolene Flore Kengne (0009-0009-3587-2697), Danielle Claude Bilanda (0000-0003-2963-9994), Leonard Tedong, Rivaldo Bernes Kahou Tadah (0009-0008-1287-8976), Pascal Emmanuel Owona (0000-0002-0233-5299), Joseph Rodrigue Ngapout Fifen, Dzeufiet Djomeni Paul Désiré (0000-0001-5315-6285), Pierre Kamtchouing (0000-0001-7544-427X)
Year2026
Volume360
Pages121181
Publication date2026-04-01
Open AccessNo
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2026.121181
PMID41548620
OpenAlexW7124430047
LanguageEN
References cited62

Acute toxicity · aqueous plant extract · Cardiotoxicity · Chronic toxicity · cytochrome P450 inhibition · Cytotoxicity · Dacryodes edulis · hepatotoxicity · herbal medicine safety · Nephrotoxicity · pharmacokinetic prediction · phytochemical screening · toxicological profile · traditional medicine validation · Medicinal Plant Research · Phytochemical Studies and Bioactivities · Phytochemistry Medicinal Plant Applications

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Highly citedNo

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