Evaluating the association between household water, sanitation and hygiene (Wash) and selected placenta-related complications in The Gambia, Kenya and Mozambique

Bibliographic Data

ID24234357
AuthorsJoseph Wells (0009-0001-1660-8681, London School of Hygiene & Tropical Medicine), Joseph Waiswa (Centre for Maternal, Reproductive, Adolescent and Child Health, London School of Hygiene and Tropical Medicine), Anifa Valá (Manhiça Health Research Centre), Bahtisen Golla (Centre for Maternal, Reproductive, Adolescent and Child Health, London School of Hygiene and Tropical Medicine), Grace Mwashigadi (0000-0002-6321-3287, Aga Khan University), Hawanatu Jah (0000-0002-4347-5247, MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine), Marleen Temmerman (0000-0003-2069-8752, Aga Khan University), Robin Okello (Aga Khan University), Isaac Mwaniki (0009-0003-1299-1657, Aga Khan University), Herminio Cossa (0000-0002-5771-2637, Manhiça Health Research Centre), Moses Mukhanya (Aga Khan University), Esperança Sevene (0000-0001-9025-4052, Manhiça Health Research Centre), Yahaya Idris (0009-0008-0228-1017, MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine), Onesmus Wanje Ziro (0000-0002-0271-2533, Aga Khan University), Angela Koech (0000-0003-4838-3269, Aga Khan University), Anna Roca (0000-0001-6034-1868, MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine), Laura Braun (0000-0001-9319-0859, London School of Hygiene & Tropical Medicine), Marie-Laure Volvert (King's College London), Fatima Touray (0000-0003-2384-4970, MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine), Umberto D’alessandro (0000-0001-6341-5009, MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine), Peter Von Dadelszen (0000-0003-4136-3070, King's College London), Warren Graham (0000-0003-1473-5342, London School of Hygiene & Tropical Medicine), Hannah Blencowe (0000-0003-1556-3159, Centre for Maternal, Reproductive, Adolescent and Child Health, London School of Hygiene and Tropical Medicine), the PRECISE and PRECISE-DYAD Networks
EditorsJulia Robinson (0000-0003-0719-3995, PLOS: Public Library of Science)
Year2026
Volume6
Issue10
Pagese0005004
Publication date2026-10-15
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0005004
OpenAlexW7222039077
LanguageEN
References cited53

Placenta-related complications contribute substantially to maternal and perinatal mortality globally, with the greatest burden in low- and middle-income countries (LMICs). However, the potential influence of inadequate household water, sanitation and hygiene (WASH) on these outcomes remains poorly characterised. We investigated associations between household WASH conditions and selected placenta-related complications, including pre-eclampsia, small-for-gestational-age (SGA) and stillbirth, in The Gambia, Kenya and Mozambique. This secondary analysis was nested within PRECISE (PREgnancy Care Integrating Translational Science, Everywhere), a prospective observational cohort of 5,745 unselected pregnant women. Multivariable modified Poisson regression with robust standard errors was used to assess associations between household WASH exposures and pre-eclampsia, SGA or stillbirth. Missing exposure and covariate data were low (

Child Nutrition and Water Access · Global Maternal and Child Health · Pregnancy and preeclampsia studies

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