Visions of a Cure
Visualization, Clinical Trials, and Controversies in Cardiac Therapeutics, 1968-1998
Bibliographic Data
| ID | 3385487 |
|---|---|
| Authors | David S Jones (0000-0003-0039-7784, Harvard University, corresponding author) |
| Year | 2000 |
| Volume | 91 |
| Issue | 3 |
| Pages | 504-541 |
| Publication date | 2000-09-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Isis (JOURNAL) |
| Journal identifiers | ISSN: 0021-1753 • E-ISSN: 1545-6994 |
| Publisher | University of Chicago Press (PUBLISHER • US) |
| DOI | 10.1086/384853 |
| PMID | 11143786 |
| OpenAlex | W2002366189 |
| Language | EN |
| Citations received | 15 |
| References cited | 1 |
In the early 1970s physicians engaged in fierce debates over the most appropriate method of evaluating the efficacy of coronary artery bypass grafting (CABG). With millions of patients and billions of dollars at stake, CABG sparked fierce controversy. Skeptics demanded that randomized controlled trials (RCTs) be performed, while enthusiasts argued that they already had visual proof of CABG's efficacy. When RCTs appeared, they did not settle the controversy. Participants simply reasserted their preconceptions, defending a trial's strengths or exploiting its flaws. The debate centered on standards of knowledge for the evaluation of therapeutic efficacy. Specifically, cardiologists and cardiac surgeons struggled to assess the relevance of different measures of therapeutic success: physiological or clinical, visual or statistical. Many factors contributed to participants' decisions, including disciplinary affiliation, traditions of research, personal experience with angiography, and assessments of the history of cardiac therapeutics. Physicians had to decide whether angiography provided a meaningful representation of the disease and its treatment or whether demonstrations of therapeutic success could come only from long-term statistical evaluation of mortality data
Cardiology · Clinical trial · Coronary artery disease · Epistemology · Intensive care medicine · Political science · Randomized controlled trial · Relevance (law · Representation (politics · Skepticism · Sociology · Vision · Health and Medical Research Impacts · Health Systems, Economic Evaluations, Quality of Life · Internal Medicine · Law · Medicine · Pharmaceutical industry and healthcare · Surgery
The Mist Tent
Spines of Steel
Ill Patient, Public Activist
Surgical Innovation and the Multiple Meanings of Randomized Controlled Trials
Learning from Mistakes
At the Limits of Cure
At the Limits of Cure
The Alchemy of Clinical Trials
John Wickham’s New Surgery
The Art and Science of Surgery
From anatomy to patient experience in pelvic floor surgery
Reading Friedan
Coronary artery disease and the contours of pharmaceuticalization
The management of enthusiasm
Historiography taking issue
| Unique citing works | 15 |
|---|---|
| Citations per year | 0,68 |
| Citation span | 2004 - 2021 (18) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 12 |