The problem with petrous? A consideration of the potential biases in the utilization ofpars petrosafor ancient DNA analysis
Datos Bibliográficos
| ID | 3919579 |
|---|---|
| Autores | Sophy Charlton (0000-0001-7487-2635, Department of Earth Sciences, Natural History Museum, London, UK, autor de correspondencia), Thomas J Booth (0000-0002-8731-818X, The Francis Crick Institute), Ian Barnes (0000-0001-8322-6918, Department of Earth Sciences, Natural History Museum, London, UK) |
| Año | 2019 |
| Volumen | 51 |
| Número | 4 |
| Páginas | 574-585 |
| Fecha de publicación | 2019-08-08 |
| Peer Reviewed | Sí |
| Open Access | Sí |
| Tipo | ARTICLE |
| Revista | World Archaeology (JOURNAL) |
| Identificadores de la revista | ISSN: 0043-8243 • E-ISSN: 1470-1375 |
| Editorial | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/00438243.2019.1694062 |
| PMID | 32405262 |
| OpenAlex | W3000680147 |
| Idioma | EN |
| Citas recibidas | 8 |
| Referencias citadas | 68 |
Advances in NGS sequencing technologies, improved laboratory protocols and new bioinformatic workflows have seen huge increases in ancient DNA (aDNA) research on archaeological materials. A large proportion of aDNA work now utilizes the petrous portion of the temporal bone (pars petrosa), which is recognized as an excellent skeletal element for long-term ancient endogenous (host) DNA survival. This has been significant due to the often low endogenous content of other skeletal elements, meaning that large amounts of sequencing are frequently required to obtain sufficient genetic coverage. However, exclusive sampling of the petrous for aDNA analysis introduces a new set of potential biases into our scientific studies - and these issues are yet to be considered by ancient DNA researchers. This paper aims to outline the possible biases of utilizing petrous bones to undertake aDNA analyses and highlight how these complications may potentially be overcome in future research
Ancient DNA · Archaeology · Biology · Computational biology · Data science · DNA · DNA sequencing · Evolutionary biology · Population · Workflow · Archaeology and ancient environmental studies · Computer Science · Forensic and Genetic Research · Forensic Anthropology and Bioarchaeology Studies · Genetics · History · Medicine · Paleontology
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| Obras citantes distintas | 8 |
|---|---|
| Citas por año | 1,14 |
| Intervalo de citas | 2019 - 2026 (8) |
| Velocidad de citación | current |
| Altamente citado | No |
| Tipos de cita | Neutras: 8 |