First in Man
The Politics and Ethics of Women in Clinical Drug Trials
Bibliographic Data
| ID | 3945507 |
|---|---|
| Authors | Owen Corrigan (0000-0002-7301-2200, corresponding author), Oonagh P Corrigan |
| Year | 2002 |
| Volume | 72 |
| Issue | 1 |
| Pages | 40-52 |
| Publication date | 2002-09-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Feminist Review (JOURNAL) |
| Journal identifiers | ISSN: 0141-7789 • E-ISSN: 1466-4380 |
| Publisher | SAGE Publications Inc (PUBLISHER) |
| DOI | 10.1057/palgrave.fr.9400055 |
| OpenAlex | W2085586896 |
| Language | EN |
| Citations received | 12 |
| References cited | 9 |
Within the world of pharmacology, the male body has traditionally been taken as the biological norm. Coupled with this, concern about danger to the unborn foetus has meant that, until very recently, 'women of childbearing potential' were routinely excluded from most of the early phases of clinical drug testing. Consequently, most drugs tested during Phase I trials were initially carried out on healthy male volunteers. During subsequent phases when drugs were tested on patients, women remained largely under-represented. As a result, some drugs prescribed for women have later been discovered to be lacking in efficacy, and women are more likely to suffer adverse drug reactions than men. The exclusion of women during the early phases of clinical drug trials has now been lifted and drugs are currently being more widely tested on women. This paper examines the differing political and ethical positions adopted by the pharmaceutical industry, drug regulators, pharmacologists, women's groups and patient activists in relation to the exclusion and inclusion of women in clinical drug trials
Alternative medicine · Clinical research · Clinical trial · Drug · Drug trial · Inclusion (mineral) · Inclusion and exclusion criteria · Pathology · Political science · Politics · Psychiatry · Sociology · Ethics in Clinical Research · Gender Studies · Internal Medicine · Law · Medicine · Pharmaceutical industry and healthcare · Sex and Gender in Healthcare
Feminist Bioethics
Gendered Logics of Biomedical Research
Using “Clinical Trial Diaries” to Track Patterns of Participation for Serial Healthy Volunteers in U.S. Phase I Studies
Female Tactics and Strategies of Intimate Partner Violence
Disadvantaged, outnumbered, and discouraged
Boundary setting in breast cancer research
Stopped hearts, amputated toes and Nasa
An Elusive Evidence Base
Risk and Emotion Among Healthy Volunteers in Clinical Trials
Challenging Assumptions About Minority Participation in US Clinical Research
Feeding and Bleeding
Equality versus Reproductive Risk
| Unique citing works | 12 |
|---|---|
| Citations per year | 0,63 |
| Citation span | 2007 - 2021 (15) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 12 |