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Strategies for prevention of mother-to-child transmission of HIV

Bibliographic Data

ID3972410
AuthorsChewe Luo (0000-0002-1412-2215, United Nations Children's Fund, corresponding author)
Year2000
Volume8
Issue16
Pages144-155
Publication date2000-01-01
Open AccessNo
TypeARTICLE
VenueReproductive Health Matters (JOURNAL)
Journal identifiersISSN: 0968-8080 • E-ISSN: 1460-9576
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1016/s0968-8080(00)90198-8
PMID11424244
OpenAlexW2096774458
LanguageEN
Citations received2
References cited40

Over 90 per cent of paediatric HIV infections are maternally acquired, most of these in sub-Saharan Africa. Mortality trends underscore the humanitarian and ethical obligation for urgent global action to protect children from HIV. With the adoption of anti-retroviral therapy in pregnancy, mother-to-child transmission rates have declined to 4-6 per cent in the USA and other industrialised countries. In low-resource settings, where most of the children are continuously being exposed to HIV, the cost of anti-retroviral therapy is prohibitive. Very few developing countries apart from Botswana, Thailand and Brazil have national policies for integration of preventive anti-retroviral therapy in antenatal clinics. This paper reviews anti-retroviral and non-anti-retroviral interventions for prevention of mother-to-child transmission of HIV. To support the health of mothers as well, it supports the implementation of a comprehensive package of care in pregnancy and post-partum, such as access to antenatal and delivery services; anti-retroviral preventive therapy; malaria treatment; family planning; multivitamin, iron and folate supplementation; counselling on feeding options; post-natal care for the child and post-partum care for the mother, and calls for a strategy for advocacy, programme communication and community mobilisation

Developing country · Economic growth · Environmental health · Family medicine · Pregnancy · Psychological intervention · Adolescent Sexual and Reproductive Health · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Nursing · Pediatrics

  • Health seeking and access to care for children with suspected dengue in Cambodia

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  • Counsellors' Perspectives on Antenatal HIV Testing and Infant Feeding Dilemmas Facing Women with HIV in Northern Tanzania

    Marina Manuela De Paoli, Rachel Manongi et al.•Reproductive Health Matters•2002

  • Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine Treatment

    Edward M Connor, Rhoda S Sperling et al.•New England Journal of Medicine•1994

  • Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda

    Open Access•Laura Guay, Laura A Guay et al.•The Lancet•1999

  • The orphan problem

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Citations per year0.08
Citation span2002 - 2007 (6)
Highly citedNo

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