Multipurpose prevention technologies for reproductive and sexual health

Bibliographic Data

ID3973001
AuthorsAlan Stone (corresponding author)
Year2014
Volume22
Issue44
Pages213-217
Publication date2014-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueReproductive Health Matters (JOURNAL)
Journal identifiersISSN: 0968-8080 • E-ISSN: 1460-9576
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1016/s0968-8080(14)44801-8
PMID25555778
OpenAlexW2034200774
LanguageEN
Citations received1
References cited16

Global statistics on unplanned pregnancies, abortions and STIs show that unprotected sex is still widely practised. More needs to be done to provide women and men with a wider choice of convenient protective options. To address this need, international efforts are focusing on developing multipurpose prevention technologies (MPTs) that address two or more indications simultaneously. These technologies would have significant advantages over single-indication products. They include inter alia novel barrier devices, drugs administered either as oral tablets or vaginal/rectal gels, drugs used in combination with medical devices, and genetically engineered organisms which secrete antimicrobial substances. As an example of progress in the MPT field, this paper describes an on-demand contraceptive/antimicrobial vaginal gel, Amphora (previously known as Acidform), now in an advanced stage of development. Clinical trials are currently being planned to find out whether this product's promising antimicrobial profile translates into protective and preventive choices

Antimicrobial · Biology · Environmental health · Family medicine · Gynecology · Health services · Human immunodeficiency virus (HIV · Intensive care medicine · Microbicide · Microbicides for sexually transmitted diseases · Population · Reproductive health · Medicine · Reproductive tract infections research

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