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Psychological and Behavioural Impact of Genetic Testing Smokers for Lung Cancer Risk

A Phase II Exploratory Trial

Bibliographic Data

ID4228745
AuthorsSaskia C Sanderson (0000-0001-8427-724X, University College London, UK,), Steve E Humphrie (0000-0002-8221-6547), Steve E Humphries (University College London, UK), Christina Hubbart (0000-0001-9576-9581, University College London, UK), Eluned Hughes (Institute for Child Health, London, UK), Michael J Jarvis (0000-0001-9238-8038), Martin J Jarvis (University College London, UK), Jon Wardle (0000-0002-1691-593X), Jane Wardle (University College London, UK)
Year2008
Volume13
Issue4
Pages481-494
Publication date2008-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Health Psychology (JOURNAL)
Journal identifiersISSN: 1359-1053 • E-ISSN: 1461-7277
PublisherSAGE Publications Inc (PUBLISHER)
DOI10.1177/1359105308088519
PMID18420756
OpenAlexW2024006092
LanguageEN
Citations received6
References cited32

The behavioural and psychological impact of genetic testing for lung cancer susceptibility was examined among smokers ( N = 61) who were randomly allocated to a GSTM1 genetic testing group (with GSTM1-missing or GSTM1-present result) or no-test control group. The GSTM1-missing (higher risk) group reported greater motivation to quit smoking, and both genetic testing groups reported lower depression than the control group at one-week follow-up ( p < .05 for all). Differences were not significant at two months follow-up. This study indicates the feasibility of much-needed research into the risks and benefits for individuals of emerging lifestyle-related genetic susceptibility tests

Depression (economics · Disease · Genetic predisposition · Genetic testing · Lung cancer · Psychiatry · BRCA gene mutations in cancer · Medicine · Nutrition, Genetics, and Disease · Psychology · School Health and Nursing Education · Clinical Psychology · Demography · Internal Medicine

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Unique citing works6
Citations per year0,4
Citation span2011 - 2017 (7)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 6

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