Did sexual behaviour differences between HIV infection and treatment groups offset the preventative biological effects of ART roll-out in Zimbabwe
Bibliographic Data
| ID | 4266927 |
|---|---|
| Authors | Sarah Gregson (0000-0003-2707-0714, Imperial College London), Constance Nyamukapa (0000-0001-6779-4069, Imperial College London) |
| Year | 2021 |
| Volume | 75 |
| Issue | 3 |
| Pages | 457-476 |
| Publication date | 2021-09-02 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Population Studies (JOURNAL) |
| Journal identifiers | ISSN: 0032-4728 • E-ISSN: 1477-4747 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/00324728.2021.1874043 |
| PMID | 33559537 |
| OpenAlex | W3127371903 |
| Language | EN |
| Citations received | 2 |
| References cited | 42 |
Declines in HIV incidence have been slower than expected during the roll-out of antiretroviral treatment (ART) services in sub-Saharan African populations suffering generalized epidemics. Using data from a population-based, open cohort HIV sero-survey (2004-13), we found evidence for initial reductions in sexual activity and multiple sexual partnerships, followed by increases during the period of ART scale-up in areas of high HIV prevalence in Manicaland, east Zimbabwe. Recent population-level increases in condom use were also recorded, but largely reflected high use by the rapidly growing proportion of HIV-infected individuals on treatment. Sexual risk behaviour increased in susceptible uninfected individuals and in untreated (and therefore more infectious) HIV-infected men, which may have slowed the decline in HIV incidence in this area. Intensified primary HIV prevention programmes, together with strengthened risk screening, referral, and support services following HIV testing, could help to maximize the impact of 'test-and-treat' programmes in reducing new infections
Antiretroviral therapy · Antiretroviral treatment · Cohort · Condom · Environmental health · Family medicine · Human immunodeficiency virus (HIV) · Incidence (geometry) · Population · Referral · Viral load · Adolescent Sexual and Reproductive Health · Demography · HIV/AIDS Research and Interventions · Immunology · Internal Medicine · Medicine · Sex work and related issues
Rates of HIV‐1 Transmission per Coital Act, by Stage of HIV‐1 Infection, in Rakai, Uganda
Retention in care under universal antiretroviral therapy for HIV-infected pregnant and breastfeeding women (‘Option B+’) in Malawi
Highly Active Antiretroviral Therapy and Sexual Risk Behavior
Remedicalizing an epidemic
How to improve the validity of sexual behaviour reporting
Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission
Heterosexual HIV-1 transmission after initiation of antiretroviral therapy
High Coverage of ART Associated with Decline in Risk of HIV Acquisition in Rural KwaZulu-Natal, South Africa
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
Unaids ‘multiple sexual partners’ core indicator
Patterns of Self-reported Behaviour Change Associated with Receiving Voluntary Counselling and Testing in a Longitudinal Study from Manicaland, Zimbabwe
Methodological problems in Aids behavioral research
| Unique citing works | 2 |
|---|---|
| Citations per year | 1 |
| Citation span | 2024 - 2025 (2) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 2 |