Lifecourse socioeconomic trajectories and C-reactive protein levels in young adults
Findings from a Brazilian birth cohort
Bibliographic Data
| ID | 4590524 |
|---|---|
| Authors | Aydin Nazmi (0000-0002-3650-4222, California Polytechnic State University), Isabel O Oliveira (0009-0008-7548-232X, Universidade Federal de Pelotas), Bernardo L Horta (0000-0001-9843-412X, Universidade Federal de Pelotas), Denise P Gigante (0000-0001-7309-5838, Universidade Federal de Pelotas), Cesar G Victora (0000-0002-2465-2180, Universidade Federal de Pelotas) |
| Year | 2010 |
| Volume | 70 |
| Issue | 8 |
| Pages | 1229-1236 |
| Publication date | 2010-04-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Social Science & Medicine (JOURNAL) |
| Journal identifiers | ISSN: 0277-9536 • E-ISSN: 1873-5347 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.socscimed.2009.12.014 |
| PMID | 20137842 |
| PMCID | PMC2877874 |
| OpenAlex | W1996639963 |
| Language | EN |
| Citations received | 13 |
| References cited | 56 |
Socioeconomic factors are associated with cardiovascular disease. C-reactive protein (CRP) is increasingly implicated as a candidate linking conventional risk factors and atherosclerosis. The impact of early- and later-life socioeconomic status (SES) on CRP levels has not been widely investigated and a handful of studies from high-income countries are inconsistent. We set out to examine the associations between lifecourse socioeconomic indicators (family income at birth, maternal education, family income at age 23 and own education) on CRP levels in young adults belonging to the 1982 Pelotas (Brazil) Birth Cohort Study (n=5914). Early-life SES showed significant and graded associations with CRP levels at age 23 independently of later SES. For example, men with higher family income at birth showed higher CRP levels at age 23 (p=0.001 for trend) and women with less educated mothers showed higher CRP levels (p=0.01 for trend). Notably, differential directions of association between SES indicators and CRP levels between men and women were found. When adjusted for SES at age 23, men with the lowest family income at birth showed 42% lower CRP levels when compared to men in the highest family income group (-42; 95% CI: -60,-16). In contrast women born to the least educated mothers had the highest CRP levels (35; 95% CI -2, 86). In both sexes, adiposity accounted for the overwhelming majority of the associations between SES and CRP levels. Sex and gender roles specific to middle-income countries, socio-cultural and environmental conditions that may impact adiposity, and the level of epidemiological transition may be key factors that are linked to the associations between lifecourse SES and CRP levels. Public health strategies aimed at decreasing the burden of cardiovascular disease in middle-income settings, in addition to highlighting the risks associated with adult obesity, should not overlook the wide-ranging impacts of lifecourse social determinants
Cohort · Cohort study · Environmental health · Population · Socioeconomic status · Sociology · Birth, Development, and Health · Body Composition Measurement Techniques · Demography · Medicine · Obesity, Physical Activity, Diet · Gerontology · Internal Medicine
Psychological stress during childhood and adolescence and its association with inflammation across the lifespan
Pathogenic and obesogenic factors associated with inflammation in Chinese children, adolescents and adults
Childhood Socioeconomic Circumstances, Inflammation, and Hemostasis Among Midlife Women
Sex Differences in Associations Between Subjective Social Status and C-Reactive Protein in Young Adults
The Long Arm of childhood hypothesis and systematic low-grade inflammation
Individual and Neighborhood Stressors, Air Pollution and Cardiovascular Disease
Childhood meat eating and inflammatory markers
Life-course origins of social inequalities in adult immune cell markers of inflammation in a developing southern Chinese population
Early life socioeconomic adversity is associated in adult life with chronic inflammation, carotid atherosclerosis, poorer lung function and decreased cognitive performance
Socioeconomic status in childhood and C reactive protein in adulthood
Multilevel examination of the association of urbanization with inflammation in Chinese adults
Gestational age and newborn size according to parental social mobility
Culture and the Immune System
Cohort Profile
Socioeconomic inequalities in cardiovascular disease mortality. An international study
Socioeconomic Status and Obesity
Socioeconomic factors and cardiovascular disease
Independent Effects of Income and Education on the Risk of Obesity in the Brazilian Adult Population
Socioeconomic differences in the prevalence of common chronic diseases
A Validity Study of a Psychiatric Screening Questionnaire (SRQ-20) in Primary Care in the city of Sao Paulo
Early-life and adult socioeconomic status and inflammatory risk markers in adulthood
Markers of Inflammation and Cardiovascular Disease
Ethnic and Socioeconomic Differences in Cardiovascular Disease Risk Factors
Trends and Disparities in Coronary Heart Disease, Stroke, and Other Cardiovascular Diseases in the United States
The Developmental Origins of Adult Disease
Fetal programming and adult health
Life-course socio-economic factors, skin colour and abdominal obesity in adulthood in a Brazilian birth cohort
Socioeconomic status and obesity
Association of markers of systemic inflammation, C reactive protein, serum amyloid A, and fibrinogen, with socioeconomic status
Income-Specific Trends in Obesity in Brazil
The Pelotas birth cohort study, Rio Grande do Sul, Brazil, 1982-2001
| Unique citing works | 13 |
|---|---|
| Citations per year | 0,87 |
| Citation span | 2011 - 2022 (12) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 13 |