Revisiting the global workspace orchestrating the hierarchical organization of the human brain
Bibliographic Data
| ID | 4616754 |
|---|---|
| Authors | Gustavo Deco (0000-0002-8995-7583, Institució Catalana de Recerca i Estudis Avançats, corresponding author), Diego Vidaurre (0000-0002-9650-2229, Aarhus University), Morten L Kringelbach (0000-0002-3908-6898, Aarhus University) |
| Year | 2021 |
| Volume | 5 |
| Issue | 4 |
| Pages | 497-511 |
| Publication date | 2021-01-04 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Nature Human Behaviour (JOURNAL) |
| Journal identifiers | ISSN: 2397-3374 • E-ISSN: 2397-3374 |
| Publisher | Springer Science and Business Media LLC (PUBLISHER) |
| DOI | 10.1038/s41562-020-01003-6 |
| PMID | 33398141 |
| OpenAlex | W3118861474 |
| Language | EN |
| Citations received | 1 |
| References cited | 135 |
A central challenge in neuroscience is how the brain organizes the information necessary to orchestrate behaviour. Arguably, this whole-brain orchestration is carried out by a core subset of integrative brain regions, a 'global workspace', but its constitutive regions remain unclear. We quantified the global workspace as the common regions across seven tasks as well as rest, in a common 'functional rich club'. To identify this functional rich club, we determined the information flow between brain regions by means of a normalized directed transfer entropy framework applied to multimodal neuroimaging data from 1,003 healthy participants and validated in participants with retest data. This revealed a set of regions orchestrating information from perceptual, long-term memory, evaluative and attentional systems. We confirmed the causal significance and robustness of our results by systematically lesioning a generative whole-brain model. Overall, this framework describes a complex choreography of the functional hierarchical organization of the human brain
Cognitive science · Data science · Human–computer interaction · Workspace · Computer Science · EEG and Brain-Computer Interfaces · Functional Brain Connectivity Studies · Neural dynamics and brain function · Neuroscience · Psychology · Artificial Intelligence
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| Unique citing works | 1 |
|---|---|
| Citations per year | 0,5 |
| Citation span | 2024 - 2024 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |