Using ancient DNA analysis in palaeopathology
A Critical Analysis of Published Papers, With Recommendations for Future Work
Dados Bibliográficos
| ID | 4636648 |
|---|---|
| Autores | C Roberts (0009-0000-6905-1728), Charlotte A Roberts (0000-0002-2259-807X, Durham University, autor correspondente), Ingham (0000-0002-7581-707X), S Ingham (Nottingham City Hospital) |
| Ano | 2008 |
| Volume | 18 |
| Fascículo | 6 |
| Páginas | 600-613 |
| Data de publicação | 2008-11-01 |
| Peer Reviewed | Sim |
| Open Access | Sim |
| Tipo | ARTICLE |
| Periódico | International Journal of Osteoarchaeology (JOURNAL) |
| Identificadores do periódico | ISSN: 1047-482X • E-ISSN: 1099-1212 |
| Editora | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/oa.966 |
| OpenAlex | W2104390567 |
| Idioma | EN |
| Citações recebidas | 21 |
| Referências citadas | 54 |
Despite an observable increase in the number of studies using ancient DNA analysis to diagnose disease in human remains, there remain issues to be addressed about the quality of the resulting publications. This paper describes the qualitative analysis of published papers that describe the detection of pathogenic DNA in human skeletal and mummified remains from archaeological sites. Its ultimate goal is to provide an overview of the main problematic issues in relationship to standards developed in molecular biology and to make recommendations for future work. Sixty-five papers published between 1993 and 2006 were surveyed and the quality of each was assessed using 15 criteria. Interesting results emerged. Of particular note was the high number of papers that did not acknowledge the use of even basic contamination control (90%) or procedures to validate results independently (85%). This study illustrates that attention to contamination control and authentication of results is needed in future research, if confidence in aDNA analysis in palaeopathology is to be increased. Additionally, methods of analysis must be described in published papers to ensure transparency in processes utilised to generate the data. Copyright (c) 2008 John Wiley & Sons, Ltd
Ancient DNA · Archaeology · Data science · Environmental health · Paleopathology · Computer Science · Forensic and Genetic Research · Forensic Entomology and Diptera Studies · History · Medicine · Yersinia bacterium, plague, ectoparasites research
The Osteological Paradox 20 Years Later
Archaeologically derived human remains in England
The Archaeology of Medicine in the Greco-Roman World
Paléopathologie et génétique
Tentative indicators of malaria in archaeological skeletal samples, a pilot study testing different methods
Collaboration of Archaeologists, Historians and Bioarchaeologists During Removal of Clothing from Korean Mummy of Joseon Dynasty
Ancient DNA (aDNA) studies of man and microbes
Deficiencies and challenges in the study of ancient tuberculosis DNA
Cats of the pharaohs
Tuberculosis on the north coast of Peru
Biomolecular archaeology of ancient tuberculosis
The challenge of identifying tuberculosis proteins in archaeological tissues
Complications in the study of ancient tuberculosis
Palaeopathology and its relevance to understanding health and disease today
Beyond dirty teeth
Tuberculosis and leprosy in perspective
Tuberculosis
Ancient pathogen genomics
Adaptation of populations to changing environments
トイレ考古学と考古寄生虫学
Biomolecular Archaeology
Identification of Mycobacterium tuberculosis DNA in a pre-Columbian Peruvian mummy.
Molecular Structure of Nucleic Acids
Ancient DNA
The use of the polymerase chain reaction (PCR) to detect Mycobacterium tuberculosis in ancient skeletons
Detection of Yersinia pestis DNA in two early medieval skeletal finds from Aschheim (Upper Bavaria, 6th century A.D.)
Real-time quantitative PCR to assess the authenticity of ancient DNA amplification
Digging deeper into the limits of ancient DNA research on syphilis
The limits of biomolecular palaeopathology
Biochemical and physical correlates of DNA contamination in archaeological human bones and teeth excavated at Matera, Italy
Osteological and Biomolecular Study of Two Possible Cases of Hypertrophic Osteoarthropathy from Mediaeval England
Authenticating DNA Extracted From Ancient Skeletal Remains
A Mediaeval Case of Lepromatous Leprosy from 13–14th Century Orkney, Scotland
Bone Preservation and Ancient DNA
Post-mortem DNA damage hotspots in Bison (Bison bison) provide evidence for both damage and mutational hotspots in human mitochondrial DNA
Detection of bone glue treatment as a major source of contamination in ancient DNA analyses
Widespread occurrence of Mycobacterium tuberculosis DNA from 18th–19th century Hungarians
Ancient DNA in anthropology
Research trends in human osteology
Brief communication
Paleopathological and biomolecular study of tuberculosis in a medieval skeletal collection from England
Brief communication
Long‐term survival of ancient DNA in Egypt
Long‐term survival of ancient DNA in Egypt
Ancient DNA Analysis of the Delta F508 Mutation
From a dry bone to a genetic portrait
Molecular evidence for different stages of tuberculosis in ancient bone samples from Hungary
Brief communication
Insights into the processes behind the contamination of degraded human teeth and bone samples with exogenous sources of DNA
DNA of Mycobacterium leprae detected by PCR in ancient bone
Confirmation of the presence of Mycobacterium tuberculosis complex-specific DNA in three archaeological specimens
Molecular identification and characterization of Mycobacterium tuberculosis complex in ancient Egyptian mummies
A first prehistoric case of tuberculosis from Britain
Ancient DNA and the archaeologist
| Obras citantes distintas | 21 |
|---|---|
| Citações por ano | 1,24 |
| Intervalo de citações | 2009 - 2023 (15) |
| Velocidade de citação | historical |
| Altamente citado | Não |
| Tipos de citação | Neutras: 19 |