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MDMA-assisted dialectical behavioral therapy for borderline personality disorder

A qualitative study of mental health clinicians

Bibliographic Data

ID4656845
AuthorsAnn M Inouye (0000-0001-9962-4996, Brown University, corresponding author), Aaron Wolfgang (0000-0002-5238-4451, Uniformed Services University of the Health Sciences), Aaron S Wolfgang, Lianne T Philhower (Chaminade University of Honolulu)
Year2024
Volume8
Issue1
Pages92-105
Publication date2024-04-10
Open AccessYes
TypeARTICLE
VenueJournal of Psychedelic Studies (JOURNAL)
Journal identifiersISSN: 2559-9283 • E-ISSN: 2559-9283
PublisherAkademiai Kiado Zrt (PUBLISHER)
DOI10.1556/2054.2023.00281
OpenAlexW4391527354
LanguageEN
References cited7

In 2021, the final series of phase 3 clinical trials looking at MDMA-AT for treatment-resistant post-traumatic stress disorder (PTSD) found that 71.2% of 3,4-methylenedioxymethamphetamine (MDMA) full-dose participants no longer met criteria for PTSD. MDMA-assisted therapy is not US Food and Drug Administration (FDA) approved in treating borderline personality disorder (BPD), and while PTSD is quite different from BPD, it is possible that some of the beneficial effects of MDMA-assisted therapy may be applicable in treating BPD. Interviewing two clinicians utilizing dialectical behavioral therapy treatment and two MDMA-assisted therapy clinicians was one way to examine the phenomenology of MDMA-assisted therapy with BPD individuals in a thoughtful manner. An exploratory, qualitative, interview-based study assessed clinicians' perspectives of MDMA-assisted therapy and BPD and increased our understanding of underlying therapeutic mechanisms and processes and the role of pharmacological factors in these treatment modalities, optimizing treatment context, and leading to improved clinical responses and patient recovery. The codes generated unique perspectives of the participants revealing a chronological narrative which included three phases of treatment

Behavioral therapy · Borderline personality disorder · Dialectic · Dialectical Behavior Therapy · MDMA · Mental health · Psychiatry · Psychotherapist · Clinical Psychology · Personality Disorders and Psychopathology · Psychedelics and Drug Studies · Psychology · Psychotherapy Techniques and Applications

  • MDMA-assisted therapy for severe PTSD

    Open Access•Jennifer M Mitchell, Michael P Bogenschutz et al.•Nature Medicine•2021

  • The safety and efficacy of ±3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder

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  • Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression

    Open Access•Fernanda Palhano-Fontes, Dayanna Barreto et al.•Psychological Medicine•2019

  • Psychedelics

    Open Access•David E Nichols•Pharmacological Reviews•2016

Highly citedNo

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