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Internet method for the extraction of N,N-dimethyltryptamine from Mimosa hostilis roots

Does it really extract dimethyltryptamine

Datos Bibliográficos

ID4685684
AutoresGiordano N Rossi (0000-0002-1952-1207, Instituto de Neurociências e Comportamento, autor de correspondencia), Eduardo José Crevelin (0000-0001-8708-147X, Universidade de São Paulo), Gabriela De Oliveira Silveira (0000-0003-2875-8764, Universidade de São Paulo), Maria Eugênia Costa Queiroz, Maria Eugênia Queiroz (0000-0002-0172-1884, Universidade de São Paulo), Mauricio Yonamine, Maurı́cio Yonamine (0000-0002-4615-1088, Universidade de São Paulo), Jaime E C Hallak (0000-0002-8784-0189, Universidade de São Paulo), Rafael Guimarães Dos Santos (0000-0001-7361-0078)
Año2019
Volumen3
Número1
Páginas1-6
Fecha de publicación2019-03-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Psychedelic Studies (JOURNAL)
Identificadores de la revistaISSN: 2559-9283 • E-ISSN: 2559-9283
EditorialAkademiai Kiado Zrt (PUBLISHER)
DOI10.1556/2054.2019.009
OpenAlexW2920742167
IdiomaEN
Citas recibidas3
Referencias citadas10

Background and aims: The psychoactive capacity of the alkaloid N,N-dimethyltryptamine (DMT) has been known for decades, and its presence in beverages used in religious contexts around the worldsuch as ayahuascahas attracted growing attention from the scientific community due to its possible anxiolytic and antidepressant effects. Mimosa hostilis, popularly known as jurema preta in Brazil, is a plant known to be utilized for extracting DMT, especially for recreational use. In this study, we confirmed if five different organic solvents (n-hexane, ethyl acetate, n-butanol, dichloromethane, and chloroform) would extract non-purified DMT from M. hostilis and compared them in terms of DMT concentration found in the five organic solvents cited before. Methods: We have performed the straight to base technique for the extraction of DMT found on the Internet. The evaluation of DMT concentration in the organic solvents was performed via UPLC-ESI-MS/MS. No investigation was performed on other compounds in the solvents. Results: All the organic solvents extracted non-purified DMT, from lower to higher concentration: n-hexane, ethyl acetate, chloroform, n-butanol, and dichloromethane. Conclusions: The Internet straight to base method indeed extracts DMT from M. hostilis roots. However, DMT is not purified and the exact composition of the extracts and its toxicology is unknown. Thus, recreational DMT users are exposing themselves to products with unknown composition and effects

Butanol · Chloroform · Chromatography · Dichloromethane · Ethanol · Ethyl acetate · Hexane · Solvent · Traditional medicine · Biochemical Analysis and Sensing Techniques · Chemistry · Medicine · Olfactory and Sensory Function Studies · Psychedelics and Drug Studies · Organic Chemistry

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    Open Access•José Carlos Bouso, Genís Ona et al.•Culture Medicine and Psychiatry•2023

  • Inhaled Dimethyltryptamine (DMT)

    Jamie E Parnes, M Earleywine•Journal of Psychoactive Drugs•2024

  • Heart rate (HR) and heart rate variability (HRV) response to inhaled N, N-dimethyltryptamine (N, N-DMT)

    Open Access•David W Lawrence•Journal of Psychedelic Studies•2022

  • Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression

    Open Access•Fernanda Palhano-Fontes, Dayanna Barreto et al.•Psychological Medicine•2019

Obras citantes distintas3
Citas por año0,75
Intervalo de citas2022 - 2024 (3)
Velocidad de citaciónrecent
Altamente citadoNo
Tipos de citaNeutras: 3
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