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Redefining Risk and Benefit

Understanding the Decision to Undergo Contralateral Prophylactic Mastectomy

Bibliographic Data

ID4693373
AuthorsKatharine A S Rendle (Palo Alto Medical Foundation Research Institute, Palo Alto, California, USA), Katharine A Rendle (0000-0002-7761-8728, Palo Alto Institute), Meghan C Halley (0000-0002-5031-9840, Palo Alto Medical Foundation Research Institute, Palo Alto, California, USA), Suepattra G May (0000-0002-7228-8440, Palo Alto Medical Foundation Research Institute, Palo Alto, California, USA), Dominick L Frosch (0000-0003-1680-0734, Gordon and Betty Moore Foundation, Palo Alto, California, USA)
Year2015
Volume25
Issue9
Pages1251-1259
Publication date2015-09-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueQualitative Health Research (JOURNAL)
Journal identifiersISSN: 1049-7323 • E-ISSN: 1552-7557
PublisherSAGE Publications Inc (PUBLISHER)
DOI10.1177/1049732314557085
PMID25371380
OpenAlexW2080835381
LanguageEN
Citations received1
References cited38

Rates of contralateral prophylactic mastectomy (CPM) among unilateral breast cancer patients are rapidly increasing; however, there are little data documenting the decision-making process of patients with no known BRCA mutations, who elect this more aggressive treatment. We conducted semistructured interviews with nine newly diagnosed patients who elected CPM over other surgical options. Using grounded theory, we analyzed interview data to identify influential decision-making factors by prevalence and intensity across participants. Decision-making factors included subjective evaluations of risk and benefit, avoidance of future breast cancer surveillance and accompanying worry, and desire to maintain (or improve) breast appearance. Based solely on survival benefit, the decision to undergo CPM might be viewed as unnecessary or even misguided. However, our findings show the importance of psychosocial factors in patients' assessments of risk and benefit, and support the need for additional patient-provider communication regarding these factors

Anxiety · Breast cancer · Cancer · Family medicine · Grounded theory · Mastectomy · Next of kin · Prophylactic Mastectomy · Psychiatry · Psychosocial · Qualitative research · Risk assessment · Worry · BRCA gene mutations in cancer · Global Cancer Incidence and Screening · Medicine · Psychology · Internal Medicine

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Unique citing works1
Citations per year1
Citation span2025 - 2025 (1)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 1

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