Predictors of fatigue in cancer patients before and after chemotherapy

Bibliographic Data

ID4898097
AuthorsM Pertl (0000-0001-7326-2763), Maria M Pertl (Trinity College Dublin), David Hevey (0000-0003-2844-0449, Trinity College Dublin), Sonya Collier (0000-0002-2205-5067, Psychological Medicine Service, St. James’s Hospital, Ireland), Kathryn Lambe (0000-0002-4799-7747, Trinity College Dublin), Anne-Marie O’dwyer (Psychological Medicine Service, St. James’s Hospital, Ireland)
Year2014
Volume19
Issue6
Pages699-710
Publication date2014-06-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Health Psychology (JOURNAL)
Journal identifiersISSN: 1359-1053 • E-ISSN: 1461-7277
PublisherSAGE Publications Inc (PUBLISHER)
DOI10.1177/1359105313477675
PMID23479299
OpenAlexW2160353039
LanguageEN
Citations received1
References cited32

Fatigue is a debilitating and common condition in cancer patients. This study examined pretreatment predictors of fatigue before chemotherapy and also assessed whether these could prospectively predict fatigue posttreatment. A total of 100 patients completed questionnaires assessing psychological factors, physical activity and sleep. A subsample of 26 participants wore actigraphs to objectively assess sleep/wake and activity/rest. Fatigue was measured pretreatment and posttreatment and at follow-up several months later. Greater pretreatment pain, depression, stress and sleep disruption significantly predicted greater fatigue before chemotherapy, explaining 55 percent of the variance. Pretreatment fatigue significantly predicted post-treatment fatigue. No other significant prospective predictors of posttreatment fatigue emerged

Cancer · Cancer-related fatigue · Chemotherapy · Depression (economics · Insomnia · Physical therapy · Prospective cohort study · Psychiatry · Sleep disorder · Cancer survivorship and care · Childhood Cancer Survivors' Quality of Life · Fibromyalgia and Chronic Fatigue Syndrome Research · Medicine · Internal Medicine