Stressful life events and depressive symptoms among symptomatic long QT syndrome patients

Bibliographic Data

ID4933254
AuthorsTaina Hintsa (0000-0003-3765-8343, IBS, Psychology, University of Helsinki, Finland), Markus Jokela (0000-0003-0117-0012, IBS, Psychology, University of Helsinki, Finland), Marko Elovainio (0000-0002-1401-1910, National Institute for Health and Welfare, Finland), Ilmari Määttänen (0000-0003-3149-6099, IBS, Psychology, University of Helsinki, Finland), Heikki Swan (Department of Cardiology, Helsinki University Central Hospital, University of Helsinki, Finland), Mirka Hintsanen (0000-0003-2673-0901, IBS, Psychology, University of Helsinki, Finland), Lauri Toivonen (Department of Cardiology, Helsinki University Central Hospital, University of Helsinki, Finland), Kimmo Kontula (0000-0001-6195-4332, University of Helsinki), Liisa Keltikangas-Jarvinen (0000-0002-7977-3852, IBS, Psychology, University of Helsinki, Finland)
Year2016
Volume21
Issue4
Pages505-512
Publication date2016-04-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Health Psychology (JOURNAL)
Journal identifiersISSN: 1359-1053 • E-ISSN: 1461-7277
PublisherSAGE Publications Inc (PUBLISHER)
DOI10.1177/1359105314530450
PMID24764285
OpenAlexW1992630653
LanguageEN
Citations received2
References cited26

We examined whether long QT syndrome status moderates the association between stressful life events and depressive symptoms. Participants were 562 ( n = 246 symptomatic) long QT syndrome mutation carriers. Depressive symptoms were measured with a modified version of the Beck's Depression Inventory. There was an interaction between long QT syndrome status and stressful life events on depressive symptoms. In the symptomatic long QT syndrome patients, stressful life events were associated with depressive symptoms ( B = 0.24, p < 0.001). In the asymptomatic long QT syndrome mutation carriers, this association was 62.5 percent weaker ( B = 0.09, p = 0.057). Compared to asymptomatic long QT syndrome mutation carriers, symptomatic long QT syndrome patients are more sensitive to the depressive effects of stressful life events

Anxiety · Asymptomatic · Beck Depression Inventory · Depression (economics · Depressive symptoms · Long QT syndrome · Psychiatry · QT interval · Cardiac electrophysiology and arrhythmias · Heart Rate Variability and Autonomic Control · Medicine · Stress Responses and Cortisol · Internal Medicine

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