Co-occurrence of malaria and Chagas disease in the Brazilian Amazon

The Need for Integrated Health Surveillance

Bibliographic Data

ID5166018
AuthorsIzabel Cristina Dos Reis (0000-0002-1961-6556, Fundação Oswaldo Cruz), Raquel Martins Lana (0000-0002-7573-1364, Barcelona Supercomputing Center), Cláudia Torres Codeço (0000-0003-1174-178X, Fundação Oswaldo Cruz), Ana Paula Dal’asta (0000-0002-1286-9067, Instituto Nacional de Pesquisas Espaciais), Milton Barbosa (0000-0003-4243-7895, Universidade Federal de Minas Gerais), Diego Ricardo Xavier (0000-0001-5259-7732, Fundação Oswaldo Cruz)
Year2025
Volume41
Issuesuppl 1
Pagese00042124-e00042124
Publication date2025-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueCadernos de Saude Publica (JOURNAL)
Journal identifiersISSN: 0102-311X • E-ISSN: 1678-4464
PublisherFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/0102-311xen042124
PMID40498943
OpenAlexW4411140662
SCIELO_PIDS0102-311X2025001401403
LanguageEN
References cited28

This study addresses the co-occurrence of malaria and Chagas disease in municipalities in the Amazon, a region characterized by geographic and climatic diversity and by socioeconomic and environmental transformations. This study aimed to identify the factors related to the co-occurrence of malaria and Chagas disease in the Brazilian Amazon from 2015 to 2019. The analysis explored 19 environmental indicators and two socioeconomic indicators related to habitat loss, land use and cover, climate anomalies, and the multidimensional poverty index. Modeling was performed by Conditional Inference Trees, adjusting models with and without contextual variables, to map areas of probable co-occurrence of the diseases. The incidence of malaria is predominant in the western Amazon, while Chagas disease is more frequent in areas of Pará and parts of Amazonas and Acre. Municipalities with high coverage of native vegetation showed higher incidences of malaria, but not necessarily of Chagas disease. Municipalities with native vegetation cover and pasture areas showed heterogeneous incidence of diseases, with some presenting a high incidence of both diseases. The predictive analysis showed an increase in the number of municipalities with a high expected incidence of malaria (moderate) and disease Chagas (high) from 1 to 7, when compared to observed data. The study showed areas with a risk of moderate and high incidence of both diseases, covering a larger region than that observed in the period. Alternatives of shared surveillance and the integration of programs for the identification of cases and treatment can be a measure to optimize resources and help eradicate these diseases in the region

Amazon rainforest · Biology · Disease · Disease surveillance · Environmental health · Geography · Incidence (geometry) · Land cover · Land use · Malaria · Population · Socioeconomic status · Ecology · Immunology · Malaria Research and Control · Medicine · Mosquito-borne diseases and control · Parasites and Host Interactions