Body fat distribution and its risk for cardiovascular events in 10 years
Brazilian Longitudinal Study of Adult Health (Elsa-Brasil)
Bibliographic Data
| ID | 5167880 |
|---|---|
| Authors | Bárbara Bruna Rodrigues De Oliveira (0000-0001-6726-9176, Universidade Federal do Ceará), Carolina Gomes Coelho (0000-0002-7294-3724, Universidade Federal de Minas Gerais), Sandhi Maria Barreto (0000-0001-7383-7811, Universidade Federal de Minas Gerais), Luana Giatti (0000-0001-5454-2460, Universidade Federal de Minas Gerais), Larissa Fortunato Araújo (0000-0001-6695-0365, Universidade Federal do Ceará) |
| Year | 2022 |
| Volume | 38 |
| Issue | 2 |
| Pages | e00346520-e00346520 |
| Publication date | 2022-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Cadernos de Saude Publica (JOURNAL) |
| Journal identifiers | ISSN: 0102-311X • E-ISSN: 1678-4464 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/0102-311x00346520 |
| PMID | 35170706 |
| OpenAlex | W4211250404 |
| SCIELO_PID | S0102-311X2022000205001 |
| Language | EN |
| References cited | 59 |
Body fat distribution seems to have different effects in cardiovascular diseases (CVD). We aimed to estimate the associations between lower limbs and trunk fat ratio and the 10-year CVD risk, and isolated risk factors in men and women. A total of 10,917 participants from ELSA-Brasil were eligible for this cross-sectional study. Associations between lower limb/trunk fat ratio with the percentage of 10-year CVD risk - according to the Framingham Risk Score - and its risk factors (systolic blood pressure, total cholesterol and HDL-cholesterol, diabetes, and use of antihypertensive medication) were performed using generalized linear models, linear and logistic regressions. All analyses were stratified by gender and adjustments were made by age, self-reported skin color, educational attainment, alcohol consumption, leisure physical activity, hypolipidemic drug use and, for women, menopausal status. In this study, 55.91% were women, with a mean age of 52.68 (SD = 6.57) years. A higher lower limb/trunk fat ratio was related to lower 10-year CVD risk, as well as a reduction in systolic blood pressure, total cholesterol, and antihypertensive drug use, also an increasing HDL-cholesterol in both genders, but this relationship was stronger in women. Besides, a protective relationship to diabetes was observed in women. Higher fat accumulation in the lower body, when compared to the trunk, seems to have a lower risk of CVD and associated risk factors - even in the presence of fat in the abdominal region - with women presenting lower risks than men
Abdominal fat · Alcohol consumption · Blood pressure · Body fat distribution · Diabetes mellitus · Framingham Heart Study · Logistic regression · Longitudinal study · Lower risk · Risk factor · Cancer Risks and Factors · Diabetes, Cardiovascular Risks, and Lipoproteins · HIV-related health complications and treatments
| Citation velocity | historical |
|---|---|
| Highly cited | No |