Pregnancy incidence, outcomes and associated factors in a cohort of women living with HIV/Aids in Rio de Janeiro, Brazil, 1996-2016
Bibliographic Data
| ID | 5168612 |
|---|---|
| Authors | Rosa Maria Soares Madeira Domingues (0000-0001-5722-8127, Fundação Oswaldo Cruz), Marcel De Souza Borges Quintana (0000-0001-5186-9791, Fundação Oswaldo Cruz), Lara Esteves Coelho (0000-0001-7154-8151, Fundação Oswaldo Cruz), Ruth Khalili Friedman (0000-0002-3330-0830, Fundação Oswaldo Cruz), Angela Cristina Vasconcelos De Andrade Rabello (0000-0003-3298-0456, Fundação Oswaldo Cruz), Vania Rocha (0000-0003-2524-9905, Fundação Oswaldo Cruz), Beatriz Gilda Jegerhorn Grinsztejn (0000-0003-3692-5155, Fundação Oswaldo Cruz) |
| Year | 2023 |
| Volume | 39 |
| Issue | 6 |
| Pages | e00232522-e00232522 |
| Publication date | 2023-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Cadernos de Saude Publica (JOURNAL) |
| Journal identifiers | ISSN: 0102-311X • E-ISSN: 1678-4464 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/0102-311xen232522 |
| PMID | 37466547 |
| OpenAlex | W4384303552 |
| SCIELO_PID | S0102-311X2023000605011 |
| Language | EN |
| References cited | 45 |
The aim of this research was to analyze pregnancy incidence and associated factors in a cohort of 753 women living with HIV/AIDS (WLWHA) in Rio de Janeiro, Brazil, from 1996 to 2016. Women aged 18-49 years who were not on menopause (surgical or natural) and did not have a tubal ligation were eligible for the study. Data were collected by medical professionals during initial and follow-up visits. Person-time pregnancy incidence rates were calculated throughout the follow-up period. Pregnancy incidence-associated factors were investigated by univariate and multiple analyzes, using an extension of the Cox survival model. Follow-up visits recorded 194 pregnancies, with an incidence rate of 4.01/100 person-years (95% CI: 3.47; 4.60). A higher pregnancy incidence was associated with CD4 nadir ≥ 350 cells/mm3, use of an antiretroviral regimen not containing Efavirenz, and prior teenage pregnancy. In turn, women with a viral load ≥ 50 copies/mL, age ≥ 35 years old, with two or more children and using a highly effective contraceptive method showed a lower incidence. Results showed a significant reduction in pregnancy incidence after 2006, a significant reduction in female sterilization from 1996 to 2016, and a high rate of cesarean sections. The association found between pregnancy incidence and the use of contraceptive methods and virological control markers suggests a good integration between HIV/AIDS and reproductive health services. The high rate of cesarean section delivery indicates the need to improve childbirth care
Antiretroviral therapy · Childbirth · Cohort · Cohort study · Efavirenz · Gynecology · Human immunodeficiency virus (HIV) · Incidence (geometry) · Obstetrics · Pregnancy · Viral load · Adolescent Sexual and Reproductive Health · Demography · Global Maternal and Child Health · HIV/AIDS Research and Interventions · Immunology · Internal Medicine · Medicine
Socioeconomic Disadvantage and Adolescent Women's Sexual and Reproductive Behavior
HIV-positive women in northeast Brazil
Repeat pregnancy in women with HIV infection in Latin America and the Caribbean
Factors associated with sterilization among HIV-positive US women in an urban outpatient clinic
Adverse pregnancy outcomes among pregnant women living with HIV in Hubei province, China
Retrospective analysis of risk factors and gaps in prevention strategies for mother-to-child HIV transmission in Rio de Janeiro, Brazil
The Intersection of HIV, Social Vulnerability, and Reproductive Health
Contemplating abortion
Uso de contracepção e desigualdades do planejamento reprodutivo das mulheres brasileiras
Pregnancy rates and predictors in women with HIV/Aids in Rio de Janeiro, Southeastern Brazil
Induced abortion during youth
Avaliação da cascata de cuidado na prevenção da transmissão vertical do HIV no Brasil
Factors associated with pregnancy and pregnancy resolution in HIV seropositive women
Reproductive choices among HIV-positive women
The pregnancy decisions of HIV-positive women
| Citation velocity | historical |
|---|---|
| Highly cited | No |